ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021
Racial and gender differences in the relationship between sarcopenia and bone mineral density among older adults.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Defining Reference Values for Skeletal Muscle Metrics on Abdominal CT Using Data From Healthy Young Adult Populations: A Systematic Review and Meta-Analysis.AJR. American journal of roentgenology · 2025Pooled it
- The relationship between hypertension and thoracic spine bone mineral density: the Multi-Ethnic Study of Atherosclerosis (MESA).BMC musculoskeletal disorders · 2026Article
- Prognostic Association of Handgrip-Defined Probable or Possible Sarcopenia Status and Polygenic Risk with 10-Year Fracture Incidence among Black, Hispanic, and White Women: A Women's Health Initiative Study.medRxiv : the preprint server for health sciences · 2026Article
- Smoking shapes the relationship between metabolic biomarkers and femoral-neck bone mineral density: A stratified analysis by smoking status.Tobacco induced diseases · 2026Article
- The obesity paradox in osteoporosis risk among older adults is mostly driven by women: a population-based prospective study.BMC geriatrics · 2025Article
- Mendelian randomization study on association between grip strength and BMD in different age groups.Journal of bone and mineral metabolism · 2024Article
- Epidemiological characteristics of traumatic spinal fractures among the elderly in China.Scientific reports · 2024Article
- Central obesity may affect bone development in adolescents: association between abdominal obesity index ABSI and adolescent bone mineral density.BMC endocrine disorders · 2024Article
- Correlation study between bone metabolic markers, bone mineral density, and sarcopenia.Journal of endocrinological investigation · 2024Article
- Longitudinal association between muscle and bone loss: Results of US and Japanese cohort studies.Journal of cachexia, sarcopenia and muscle · 2024Article
- Association of sarcopenia with osteoporosis in Chinese patients with type 2 diabetes.BMC musculoskeletal disorders · 2024Article
- The Longitudinal Association between Multiple Frailty Criteria and Depressive Symptomatology Five Years Later in Older Adults: A Decision Tree Modelling Approach.Journal of clinical medicine · 2024Article
- Skeletal muscle index together with body mass index is associated with secondary osteoporosis in patients with rheumatoid arthritis.European journal of medical research · 2024Article
- Review
- Associations between blood manganese levels and sarcopenia in adults: insights from the National Health and Nutrition Examination Survey.Frontiers in public health · 2024Article
- A Novel MRI-Based Paravertebral Muscle Quality (PVMQ) Score for Evaluating Muscle Quality and Bone Quality: A Comparative Study with the VBQ Score.Clinical interventions in aging · 2024Article
- Comparison of the utility of SARC-F, SARC-CalF, and calf circumference as screening tools for sarcopenia in patients with osteoporosis.PloS one · 2024Article
- Low physical activity and depression are the prominent predictive factors for falling in older adults: the Birjand Longitudinal Aging Study (BLAS).BMC geriatrics · 2023Article
- Association between the ratio of serum creatinine to cystatin C and bone mineral density in middle-aged and older adults: a cross-sectional study from NHANES database.The Journal of international medical research · 2023Article
- Associations between weight-adjusted waist index and bone mineral density: results of a nationwide survey.BMC endocrine disorders · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Both sarcopenia and low bone mineral density (BMD) have become public health concerns. We found that presarcopenic and/or sarcopenic individuals were more likely to have lower BMD. And this relationship has race and sex-specific discrepancy. PURPOSE: The purpose of the study was to investigate the racial and gender differences in the relationship between sarcopenia and BMD among older adults.
methodsTotally, 5476 subjects (mean age = 65.7 ± 6.4) of non-Hispanic White (n = 3297), non-Hispanic Black (n = 1265), and non-Hispanic Asian (n = 914) were analyzed. Sarcopenia was defined according to the revised European consensus on definition and diagnosis of sarcopenia (EWGSOP2). General linear model and multivariable linear regression model were used to examine the relationship between sarcopenia and regional/whole body BMD stratified by race and sex. Adjustments were conducted for physiological, behavioral, and disease factors.
resultsComparing with normal older participants, presarcopenic and sarcopenic elderly were more likely to have lower BMD. Although the difference was not statistically significant in a few sub-groups, among the three racial groups, the strongest association between sarcopenia and BMD was found in non-Hispanic Black people, followed by non-Hispanic White people and non-Hispanic Asian people. In addition, significant differences of BMD across sarcopenia stages were found in more sub-groups in women than in men after adjusting for covariates.
conclusionsIn this older cohort, sarcopenia is significantly related to low regional/whole-body BMD, and these associations vary by race and sex. Consideration in race and sex is warranted when developing strategies to maintain or minimize BMD loss.
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