ArticleGigaScience2020
Chromosomal genome of Triplophysa bleekeri provides insights into its evolution and environmental adaptation.
Article in GigaScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 40 citations in OpenAlex.
- Sympatric Speciation of Tibetan Loaches (Ecology and evolution · 2026Article
- High-Resolution Chromosome-Level Genome Assembly and Annotation of Triplophysa stewarti, an Endemic Plateau Loach from the Qinghai-Tibet Plateau.Scientific data · 2026Article
- Article
- Chromosome-level genome assembly and population genomic analysis provide insights into the genetic diversity and adaption of Schizopygopsis younghusbandi on the Tibetan Plateau.Integrative zoology · 2025Article
- Genomic-based revelation of genetic structure and adaptive characterization of Schizopygopsis malacanthus in the Jinsha River and Yalong River.BMC genomics · 2025Article
- Chromosome-level genome assembly of starry flounder (Platichthys stellatus).Scientific data · 2025Article
- Chromosome-scale assembly of Artemia tibetiana genome, first aquatic invertebrate genome from Tibet Plateau.Scientific data · 2025Article
- Whole-genome relaxed selection and molecular constraints in Triplophysa under adapted Qinghai-Tibetan Plateau.BMC genomics · 2025Article
- Chromosome-level genome assembly of Triplophysa bombifrons using PacBio HiFi sequencing and Hi-C technologies.Scientific data · 2024Article
- A chromosome-scale reference genome assembly for Triplophysa lixianensis.Scientific data · 2024Article
- Chromosome-Level Genome Assembly ofInternational journal of molecular sciences · 2024Article
- The loach haplotype-resolved genome and the identification of Mex3a involved in fish air breathing.Cell genomics · 2024Article
- Genome-Wide Identification, Expression and Response to Estrogen of Vitellogenin Gene Family in Sichuan Bream (International journal of molecular sciences · 2024Article
- The complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2024Article
- The Role of Introgression During the Radiation of Endemic Fishes Adapted to Living at Extreme Altitudes in the Tibetan Plateau.Molecular biology and evolution · 2023Article
- Review
- Chromosome-level genome assemblies of four wild peach species provide insights into genome evolution and genetic basis of stress resistance.BMC biology · 2022Article
- Contrasting population differentiation in two sympatricFrontiers in genetics · 2022Article
- Genome and population evolution and environmental adaptation ofZoological research · 2021Article
- Chromosomal genome of Triplophysa bleekeri provides insights into its evolution and environmental adaptation.GigaScience · 2020Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntense stresses caused by high-altitude environments may result in noticeable genetic adaptions in native species. Studies of genetic adaptations to high elevations have been largely limited to terrestrial animals. How fish adapt to high-elevation environments is largely unknown. Triplophysa bleekeri, an endemic fish inhabiting high-altitude regions, is an excellent model to investigate the genetic mechanisms of adaptation to the local environment. Here, we assembled a chromosomal genome sequence of T. bleekeri, with a size of ∼628 Mb (contig and scaffold N50 of 3.1 and 22.9 Mb, respectively). We investigated the origin and environmental adaptation of T. bleekeri based on 21,198 protein-coding genes in the genome.
resultsCompared with fish species living at low altitudes, gene families associated with lipid metabolism and immune response were significantly expanded in the T. bleekeri genome. Genes involved in DNA repair exhibit positive selection for T. bleekeri, Triplophysa siluroides, and Triplophysa tibetana, indicating that adaptive convergence in Triplophysa species occurred at the positively selected genes. We also analyzed whole-genome variants among samples from 3 populations. The results showed that populations separated by geological and artificial barriers exhibited obvious differences in genetic structures, indicating that gene flow is restricted between populations.
conclusionsThese results will help us expand our understanding of environmental adaptation and genetic diversity of T. bleekeri and provide valuable genetic resources for future studies on the evolution and conservation of high-altitude fish species such as T. bleekeri.
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