Evidence map›Paper›PMID 33231642›Full record

ArticleNucleic acids research2021

Mouse Genome Database (MGD): Knowledgebase for mouse-human comparative biology.

Judith A Blake, Richard Baldarelli, James A Kadin, Joel E Richardson, Cynthia L Smith, Carol J Bult, Mouse Genome Database Group

Abstract readComparative Study
In one paragraph

Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 252 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
252citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

252 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  9. Article
  10. Genetic interconnections between personality-related phenotypes and psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2026
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192 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Judith A BlakeThe Jackson Laboratory, Bar Harbor, ME, USA.
Richard BaldarelliThe Jackson Laboratory, Bar Harbor, ME, USA.
James A KadinThe Jackson Laboratory, Bar Harbor, ME, USA.
Joel E RichardsonThe Jackson Laboratory, Bar Harbor, ME, USA.
Cynthia L SmithThe Jackson Laboratory, Bar Harbor, ME, USA.
Carol J BultThe Jackson Laboratory, Bar Harbor, ME, USA.
Mouse Genome Database Group

Funding

SOFTWARE AND DATABASE SYSTEM DEVELOPMENTP41HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1995 to 2010
$72.1M
Mouse Genome DatabaseU41HG000330 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A, BULT, CAROL J · 2011 to 2020
$45.5M
Mouse Genome Database (MGD): A Core Knowledge Resource for Functional Characterization of the Human GenomeU24HG000330 · NHGRI · JACKSON LABORATORY · PI CAROL J BULT, Cynthia Louise Smith · 2021 to 2026
$20.5M
Diversity Action Plan for Mouse Genome DatabaseR25HG007053 · NHGRI · JACKSON LABORATORY · PI BULT, CAROL J · 2013 to 2020
$558k
NHGRI NIH HHS P41 HG000330NHGRI NIH HHS R25 HG007053NHGRI NIH HHS U24 HG000330NHGRI NIH HHS U41 HG000330
6 · The paper itself

Abstract

The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the community model organism knowledgebase for the laboratory mouse, a widely used animal model for comparative studies of the genetic and genomic basis for human health and disease. MGD is the authoritative source for biological reference data related to mouse genes, gene functions, phenotypes and mouse models of human disease. MGD is the primary source for official gene, allele, and mouse strain nomenclature based on the guidelines set by the International Committee on Standardized Nomenclature for Mice. MGD's biocuration scientists curate information from the biomedical literature and from large and small datasets contributed directly by investigators. In this report we describe significant enhancements to the content and interfaces at MGD, including (i) improvements in the Multi Genome Viewer for exploring the genomes of multiple mouse strains, (ii) inclusion of many more mouse strains and new mouse strain pages with extended query options and (iii) integration of extensive data about mouse strain variants. We also describe improvements to the efficiency of literature curation processes and the implementation of an information portal focused on mouse models and genes for the study of COVID-19.

Indexed as

Databases, GeneticKnowledge BasesAnimalsCOVID-19Data CurationDisease Models, AnimalEpidemicsGene OntologyGenomeGenomicsHumansInformation Storage and RetrievalInternetMiceSARS-CoV-2

Identifiers

PMID33231642
PMCPMC7779030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.