ArticleChembiochem : a European journal of chemical biology2021
How To Quantify a Genetic Firewall? A Polarity-Based Metric for Genetic Code Engineering.
Article in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- The promise and peril of mirror bacteria.Acta biochimica Polonica · 2026Article
- Microbial engineering for sustainable microplastic biodegradation: from enzyme redesign to synthetic consortia.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Review
- Genetic Code-Locking Confers Stable Virus Resistance to a Recoded Organism.Biochemistry · 2025Article
- Engineering biology applications for environmental solutions: potential and challenges.Nature communications · 2025Review
- Xenobiology for the Biocontainment of Synthetic Organisms: Opportunities and Challenges.Life (Basel, Switzerland) · 2024Review
- Article
- Refactored genetic codes enable bidirectional genetic isolation.Science (New York, N.Y.) · 2022Article
- Bottlenecks and opportunities for synthetic biology biosafety standards.Nature communications · 2022Article
- How To Quantify a Genetic Firewall? A Polarity-Based Metric for Genetic Code Engineering.Chembiochem : a European journal of chemical biology · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Genetic code engineering aims to produce organisms that translate genetic information in a different way from that prescribed by the standard genetic code. This endeavor could eventually lead to genetic isolation, where an organism that operates under a different genetic code will not be able to transfer functional genes with other living species, thereby standing behind a genetic firewall. It is not clear however, how distinct the code should be, or how to measure the distance. We have developed a metric (Δ
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.