Evidence map›Paper›PMID 33230857›Full record

ArticleJournal of medical virology2021

No SARS-CoV-2 carriage observed in children attending daycare centers during the intial weeks of the epidemic in Belgium.

Stefanie Desmet, Esra Ekinci, Ine Wouters, Bram Decru, Kurt Beuselinck, Surbhi Malhotra-Kumar, Heidi Theeten

Abstract read
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. SARS-CoV-2 Circulation in the School Setting: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Limited role of children in transmission of SARS-CoV-2 virus in households-Immunological analysis of 26 familial clusters.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2023
    Article
  6. Article
  7. Detection of SARS-CoV-2 in young children attending day-care centres in Belgium, May 2020 to February 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  8. Transmission of SARS-CoV-2 by children: a rapid review, 30 December 2019 to 10 August 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Review
  9. Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefanie DesmetKU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, Campus Gasthuisberg, Leuven, Belgium.
Esra EkinciCentre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Wilrijk, Belgium.ORCID 0000-0003-1101-5681
Ine WoutersCentre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Wilrijk, Belgium.
Bram DecruKU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, Campus Gasthuisberg, Leuven, Belgium.
Kurt BeuselinckDepartment of Laboratory Medicine and National Reference Centre for Respiratory Pathogens, University Hospitals Leuven, Leuven, Belgium.
Surbhi Malhotra-KumarLaboratory for Medical Microbiology, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Wilrijk, Belgium.
Heidi TheetenCentre for the Evaluation of Vaccination, Vaccine and Infectious Disease Institute, University of Antwerp, Campus Drie Eiken, Wilrijk, Belgium.

Funding

Fonds Wetenschappelijk Onderzoek 1150017NFonds Wetenschappelijk Onderzoek 1523518NKU Leuven
6 · The paper itself

Abstract

To gain knowledge about the role of young children attending daycare in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic, a random sample of children (n = 84) aged between 6 and 30 months attending daycare in Belgium was studied shortly after the start of the epidemic (February 29th) and before the lockdown (March 18th) by performing in-house SARS-CoV-2 real-time polymerase chain reaction. No asymptomatic carriage of SARS-CoV-2 was detected, whereas common cold symptoms were common (51.2%). Our study shows that in Belgium, there was no sign of early introduction into daycare centers at the moment children being not yet isolated at home, although the virus was clearly circulating. It is clear that more evidence is needed to understand the actual role of young children in the transmission of SARS-CoV-2 and their infection risk when attending daycare.

Indexed as

BelgiumCarrier StateChild Day Care CentersChild, PreschoolCOVID-19HumansInfantReal-Time Polymerase Chain ReactionSARS-CoV-2carriagechildrenCOVID-19daycareSARS-COV-2

Identifiers

PMID33230857
PMCPMC7753838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.