Evidence map›Paper›PMID 33230758›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

A serial SPECT-CT study in a celiac disease patient with cerebellar ataxia and psychiatric symptoms.

Juliana J Schmidt, Guilherme J Schmidt, Julio C Tolentino, Eunice N Simoes, Angela Obongo, Yolanda Tolentino, Francisco A Coelho, Maria C P P Landesmann, Lea M B Fonseca, Glenda C B Lacerda and 1 more

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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Juliana J SchmidtDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil. julianaschmidtjaneiro@gmail.com.ORCID http://orcid.org/0000-0002-3949-2984
Guilherme J SchmidtDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Julio C TolentinoDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Eunice N SimoesDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Angela ObongoDepartment of Public Health, University of Brandenburg of Technology Cottbus, Senftenberg, Germany.
Yolanda TolentinoDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Francisco A CoelhoDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Maria C P P LandesmannDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Lea M B FonsecaDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Glenda C B LacerdaDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Sergio L SchmidtDepartment of Neurology, Federal University of the State of Rio de Janeiro, Mariz and Barros street, 775, Tijuca, Rio de Janeiro, RJ, 202709-001, Brazil.
Universidade Federal do Estado do Rio de Janeiro · BRUniversidade Federal do Rio de Janeiro · BRBrandenburg University of Technology Cottbus-Senftenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is an immune-mediated systemic disorder triggered by gluten and related prolamins in genetically predisposed individuals. Here, we described a case of a 31-year-old Caucasian woman who exhibited cerebellar and psychiatric dysfunctions. The patient underwent single-photon emission computed tomography (SPECT-CT) before and after a gluten-free diet (GFD). There was an improvement in cerebellar perfusion accompanied by a remission of cerebellar manifestations. The maintenance of the psychiatric manifestations was related to the persistence of the hypoperfusion in the frontal lobes. The patient's psychiatric symptoms did not change after 4 months under a GFD in the hospital. To our knowledge, this is the first case that shows the relationship between improvement in cerebellar perfusion and remission of cerebellar clinical manifestations in a CD patient under a GFD.

Indexed as

Celiac DiseaseCerebellar AtaxiaAdultDiet, Gluten-FreeFemaleHumansTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedCeliac diseaseCerebellar perfusionCerebellumSPECT-CT

Identifiers

PMID33230758
OpenAlexW3109509112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.