Evidence map›Paper›PMID 33230755›Full record

SynthesisCurrent hypertension reports2020

Electronic Cigarette Use and Blood Pressure Endpoints: a Systematic Review.

Irene Martinez-Morata, Tiffany R Sanchez, Daichi Shimbo, Ana Navas-Acien

Registry-linked trialOpen access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Current hypertension reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06019910 (The Effects of Snus on Home Blood Pressure and Metabolism), which is not on this map. Cited by 29 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 9 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06019910 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Effects of Snus on Home Blood Pressure and Metabolism

TypeinterventionalSponsorUniversity Hospital, LinkoepingRan2023 to 2024Enrolled28ConditionsBlood Pressure, Dyslipidemias, Dysglycemia, ObesityArmsSnus with or without tobacco
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 9 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2025
    Pooled it
  3. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2024
    Pooled it
  4. Pooled it
  5. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Health Effects of Electronic Cigarettes: An Umbrella Review and Methodological Considerations.International journal of environmental research and public health · 2022
    Pooled it
  7. Pooled it
  8. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021
    Pooled it
  9. Electronic cigarettes for smoking cessation.The Cochrane database of systematic reviews · 2021
    Pooled it
  10. Trial
  11. Article
  12. Article
  13. Advances in Hypertension Management: Insights from the Latest European Guidelines.Journal of cardiovascular development and disease · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Irene Martinez-MorataDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University Irving Medical Center, 722 West 168th Street, New York, NY, 10032, USA. im2557@cumc.columbia.edu.
Tiffany R SanchezDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University Irving Medical Center, 722 West 168th Street, New York, NY, 10032, USA.
Daichi ShimboDepartment of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University Irving Medical Center, 722 West 168th Street, New York, NY, 10032, USA. an2737@cumc.columbia.edu.ORCID 0000-0001-9824-7797
Columbia University Irving Medical Center · USColumbia University · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Metal Exposure and Early Cardiovascular Risk in Adult E-Cigarette UsersR01ES029967 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NAVAS-ACIEN, ANA, SHIMBO, DAICHI · 2020 to 2024
$3.4M
NCATS NIH HHS KL2 TR001874NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES029967NIEHS NIH HHS R01ES029967NIH HHS P30ES009089
6 · The paper itself

Abstract

purpose of reviewE-cigarettes (e-cigs) release toxic chemicals known to increase blood pressure (BP) levels. The effects of e-cigs on BP, however, remain unknown. Studying BP may help characterize potential cardiovascular risks of short- and long-term e-cig use. We summarized published studies on the association of e-cig use with BP endpoints. RECENT

findingsThirteen e-cig trials (12 cross-over designs) and 1 observational study evaluated systolic and diastolic blood pressure (SBP and DBP). All trials included at least one e-cig arm with nicotine, 6 a no-nicotine e-cig arm, and 3 a placebo arm. SBP/DBP increased in most nicotine e-cig arms, in some non-nicotine e-cig arms, and in none of the placebo arms. The observational study followed e-cig users and nonsmokers for 3.5 years with inconsistent findings. The use of e-cigs with and without nicotine may result in short-term elevations of both SBP and DBP. Prospective studies that investigate the long-term cardiovascular impact of e-cig use are needed.

Indexed as

Electronic Nicotine Delivery SystemsHypertensionVapingBlood PressureHumansObservational Studies as TopicProspective StudiesBlood pressureElectronic-cigarettesHypertensionNicotine

Identifiers

PMID33230755
PMCPMC10867863
OpenAlexW3110546029

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.