Evidence map›Paper›PMID 33230743›Full record

Trial reportClinical oral investigations2021

Are recent available blended collagen-calcium phosphate better than collagen alone or crystalline calcium phosphate? Radiotextural analysis of a 1-year clinical trial.

Tomasz Wach, Marcin Kozakiewicz

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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  6. Measures of Corticalization.Journal of clinical medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tomasz WachDepartment of Maxillofacial Surgery, Medical University in Lodz, Pl. Hallera 1, 90-647, Łódź, Poland. tomaszwach.90@gmail.com.ORCID http://orcid.org/0000-0003-4763-8354
Marcin KozakiewiczDepartment of Maxillofacial Surgery, Medical University in Lodz, Pl. Hallera 1, 90-647, Łódź, Poland.
Medical University of Lodz · PL

Funding

Uniwersytet Medyczny w Lodzi 503/5-061-02/503-51-001-17Uniwersytet Medyczny w Lodzi 503/5-061-02/503-51-001-18Uniwersytet Medyczny w Lodzi 503/5-061-02/503-51-002-18
6 · The paper itself

Abstract

objectivesThe purpose of this study is to compare bone regeneration properties of recently available collagen-calcium phosphate (C-CP) blend as bone substitute (BS) material in oral surgery with calcium phosphate (CP) as well as collagen material (Collagen). Is C-CP better than the classic loose CP, or is it at least equally effective in the jawbone regeneration with the superiority of a coherent consistency? MATERIALS AND

methodsThis study included 102 patients during 12-month follow-up. All patients underwent the following surgical procedures: sinus lift (52patients) and tooth extraction (50patients). Patients were divided into 3 groups which are as follows: experimental group with C-CP, CP and pure Collagen as control groups. Texture analysis was performed in intra-oral radiographs. Analyses were performed in the MaZda 4.6 software. Average 2444-pixel ROIs were established in the image of BS materials and normal trabecular bone for texture comparison to evaluate the jawbone regeneration process. Four features were calculated and investigated.

resultsTexture analyses revealed that all 4 features described the healing process well. Reference textural value of feature SumOfSqrs < 102.37 was soft tissue, DifEntr < 1.1 was not the bone, Entr < 2.62 was not a bone and LngREmph > 1.8 was soft tissue. For 12 months, bone regeneration was proved by 3 of 4 investigated features. Only Entr indicated to CP remnants in the ROI (p < 0.05).

conclusionsThis study proves that blended collagen-calcium phosphate as a BS material can bring satisfactory and predictable outcomes in jawbone regeneration. CLINICAL RELEVANCE: Clinicians can choose a satisfactory and predictable material for bone regeneration treatment.

Indexed as

Bone SubstitutesCalcium PhosphatesBone RegenerationCollagenHumansWound HealingBone SubstitutesCalcium PhosphatesCollagenBone regenerationCalcium phosphatesCollagenOsteoconduction

Identifiers

PMID33230743
OpenAlexW3109135885

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.