Evidence map›Paper›PMID 33230510›Full record

ArticleEJHaem2020

COVID-19 and the pulmonary complications of sickle cell disease.

Thivya Sivalingam, Baba Inusa, Pat Doyle, Eugene Oteng-Ntim

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Thivya SivalingamFaculty of Life Sciences and Medicine GKT School of Medicine King's College London London UK.ORCID https://orcid.org/0000-0003-4836-448X
Baba InusaDepartment of Paediatrics Evelina Children's Hospital, Guy's and St Thomas' Hospital NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0003-2643-765X
Pat DoyleDepartment of Non-communicable Disease Epidemiology London School of Hygiene and Tropical Medicine Faculty of Epidemiology and Population Health London UK.
Eugene Oteng-NtimDepartment of Obstetrics and Gynaecology Guy's and St Thomas' Hospital NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0001-8867-2909
St Thomas' Hospital · GBKing's College London · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell disease (SCD) patients are commonly affected by pulmonary complications such as acute chest syndrome (ACS), pulmonary embolism (PE) and pneumonia that contribute to significant mortality risks. With a greater susceptibility to infection, they are deemed to be vulnerable patients during the current COVID-19 pandemic. In emerging small case studies of SCD patients with COVID-19 and further complicated by pneumonia, ACS, and/or PE, the clinical benefits of early exchange transfusion and Tocilizumab are evident. However, further clinical trials and larger cohort studies are essential to evaluate effective diagnostic and management options for this high-risk group.

Indexed as

infectionsickle cell anemiasickle cell diseasetherapyviruses

Identifiers

PMID33230510
PMCPMC7675298
OpenAlexW3092271204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.