Evidence map›Paper›PMID 33230233›Full record

ArticleScientific reports2020

Impact of deranged B cell subsets distribution in the development of HCV-related cirrhosis and HCC in type two diabetes mellitus.

Fadwa A Abdelwahab, Khaled M Hassanein, Helal F Hetta, Mohamed O Abdelmalek, Asmaa M Zahran, Omnia El-Badawy

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Cellular based immunotherapy for primary liver cancer.Journal of experimental & clinical cancer research : CR · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Fadwa A AbdelwahabAssiut Health Administration, Assiut, Egypt.
Khaled M HassaneinMedical Microbiology and Immunology Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt.
Helal F HettaMedical Microbiology and Immunology Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt.ORCID 0000-0001-8541-7304
Mohamed O AbdelmalekTropical Medicine and Gastroenterology Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Asmaa M ZahranDepartment of Clinical Pathology, South Egypt Cancer Institute, Assiut University, Assiut, Egypt.
Omnia El-BadawyMedical Microbiology and Immunology Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt. omniaalbadawy@aun.edu.eg.ORCID 0000-0001-8445-711X
Assiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type II diabetes (T2D) may worsen the course of hepatitis C virus infection with a greater risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). In chronic viral infections, the deranged B cell subset signifies uncontrolled disease. The study aimed to verify the relation between B cell subsets' distribution and liver disease progression in chronic hepatitis C (CHC) patients with T2D. A total of 67 CHC patients were divided into two groups; 33 non-diabetic and 34 with T2D. Each group was subdivided into CHC-without LC or HCC (N-CHC), CHC-with LC (CHC-LC), and CHC-with HCC (CHC-HCC). Twenty-seven healthy individuals also participated as controls. Flow cytometry was used to analyze CD19

Indexed as

ADP-ribosyl Cyclase 1AdultAgedAntigens, CD19B-Lymphocyte SubsetsCarcinoma, HepatocellularCase-Control StudiesCD24 AntigenDiabetes Mellitus, Type 2FemaleGene ExpressionHepacivirusHepatitis C, ChronicHumansImmunologic MemoryImmunophenotypingADP-ribosyl Cyclase 1Antigens, CD19CD19 molecule, humanCD24 AntigenCD24 protein, humanCD38 protein, humanMembrane Glycoproteins

Identifiers

PMID33230233
PMCPMC7683559
OpenAlexW3110270233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.