Evidence map›Paper›PMID 33230191›Full record

ArticleScientific reports2020

Feed additives for the control of post-weaning Streptococcus suis disease and the effect on the faecal and nasal microbiota.

Florencia Correa-Fiz, Carlos Neila-Ibáñez, Sergio López-Soria, Sebastian Napp, Blanca Martinez, Laia Sobrevia, Simon Tibble, Virginia Aragon, Lourdes Migura-Garcia

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Analysis of the Nasal Microbiota in Healthy and Diseased Pigs.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  9. Article
  10. Prevalence ofOne health (Amsterdam, Netherlands) · 2023
    Review
  11. Why Veterinarians (Do Not) Adhere to the Clinical PracticeAntibiotics (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. From Farm to Fork:Viruses · 2022
    Review
  15. Resistance ofAntibiotics (Basel, Switzerland) · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Stochastic Assessment of the Economic Impact ofFrontiers in veterinary science · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Florencia Correa-FizIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Carlos Neila-IbáñezIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Sergio López-SoriaIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Sebastian NappIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Blanca MartinezASN SL, Calle de Murcia, PL Fraga, 22520, Huesca, Spain.
Laia SobreviaASN SL, Calle de Murcia, PL Fraga, 22520, Huesca, Spain.
Simon TibbleASN SL, Calle de Murcia, PL Fraga, 22520, Huesca, Spain.
Virginia AragonIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
Lourdes Migura-GarciaIRTA, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. lourdes.migura@irta.cat.
Universitat Autònoma de Barcelona · ESServicio Murciano de Salud · ESCentre de Recerca en Sanitat Animal · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicated feed is a common strategy to control the occurrence of Streptococcus suis disease in swine production, but feed additives may constitute an alternative to metaphylaxis. In a farm with post-weaning S. suis disease, the following additives were tested: lysozyme (Lys), medium chain fatty acids plus lysozyme (FA + Lys), FA plus a natural anti-inflammatory (FA + antiinf) and amoxicillin (Amox). During the course of the study, FA + antiinf and Amox groups showed lower prevalence of clinical signs compatible with S. suis disease than the rest of the groups. Piglets from the FA + antiinf group showed high diversity and richness in their nasal and faecal microbiota. Diet supplements did not have major effects on the faecal microbiota, where the genus Mitsuokella was the only differentially present in the FA + Lys group. In the nasal microbiota, piglets from FA + antiinf presented higher differential abundance of a sequence variant from Ruminococcaceae and lower abundance of an unclassified genus from Weeksellaceae. In general, we detected more significant changes in the nasal than in the feacal microbiota, and found that parity of the dams affected the microbiota composition of their offspring, with piglets born to gilts exhibiting lower richness and diversity. Our results suggest that additives could be useful to control post-weaning disease when removing antimicrobials in farms.

Indexed as

WeaningAgricultureAmoxicillinAnimal FeedAnimalsAnti-Infective AgentsDietary SupplementsDNA, BacterialFatty AcidsFecesFemaleFood AdditivesMicrobiotaMuramidaseNasal MucosaParityAmoxicillinAnti-Infective AgentsDNA, BacterialFatty AcidsFood AdditivesMuramidase

Identifiers

PMID33230191
PMCPMC7683732
OpenAlexW3107498476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.