Evidence map›Paper›PMID 33230154›Full record

ArticleScientific reports2020

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa.

Ayat Zagzoog, Kawthar A Mohamed, Hye Ji J Kim, Eunhyun D Kim, Connor S Frank, Tallan Black, Pramodkumar D Jadhav, Larry A Holbrook, Robert B Laprairie

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 165 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. (+)-Trans-Cannabidiol Is an Agonist at Human CBPharmacology research & perspectives · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Pharmacokinetic and pharmacodynamic properties of cannabigerol in male mice.The Journal of pharmacology and experimental therapeutics · 2026
    Article
  10. Article
  11. The Pharmacological Profile of Plant-Derived Cannabinoids In Vitro.Current topics in behavioral neurosciences · 2026
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ayat ZagzoogCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Kawthar A MohamedCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Hye Ji J KimCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Eunhyun D KimCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Connor S FrankCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Tallan BlackCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada.
Pramodkumar D JadhavAurora Prairie Research Centre, Aurora Cannabis, Saskatoon, SK, Canada.
Larry A HolbrookZYUS Life Sciences, Saskatoon, SK, Canada.
Robert B LaprairieCollege of Pharmacy and Nutrition, University of Saskatchewan, 3B36, Health Sciences Building, 107 Wiggins Road, Saskatoon, SK, S7N 2Z4, Canada. robert.laprairie@usask.ca.
University of Saskatchewan · CADalhousie University · CAGenome Prairie · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of ∆

Indexed as

AnalgesicsAnimalsAnti-Anxiety Agentsbeta-Arrestin 2CannabidiolCannabinoid Receptor AgonistsCannabinoidsCannabisCHO CellsCricetulusDronabinolGene ExpressionHumansMice, Inbred C57BLPlant ExtractsPsychotropic DrugsAnalgesicsAnti-Anxiety Agentsbeta-Arrestin 2cannabichromeneCannabidiolcannabidiolic acidcannabidivarincannabigerolCannabinoid Receptor AgonistsCannabinoidsdelta(9)-tetrahydrocannabinolic acidDronabinolPlant ExtractsPsychotropic DrugsReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2tetrahydrocannabivarin 9

Identifiers

PMID33230154
PMCPMC7684313
OpenAlexW3109480914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.