Evidence map›Paper›PMID 33230146›Full record

ArticleNature communications2020

Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life.

Hongjun Yu, Dominik K Haja, Gerrit J Schut, Chang-Hao Wu, Xing Meng, Gongpu Zhao, Huilin Li, Michael W W Adams

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Molecular and energetic basis of histidine switch dynamics in respiratory complex I.Protein science : a publication of the Protein Society · 2026
    Article
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  6. Article
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  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Functional Dynamics of an Ancient Membrane-Bound Hydrogenase.Journal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Hongjun Yu *Structural Biology Program, Van Andel Institute, Grand Rapids, MI, USA.
Dominik K Haja *Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.
Gerrit J SchutDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.
Chang-Hao WuDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.
Xing MengStructural Biology Program, Van Andel Institute, Grand Rapids, MI, USA.
Gongpu ZhaoStructural Biology Program, Van Andel Institute, Grand Rapids, MI, USA.ORCID http://orcid.org/0000-0003-0330-1581
Huilin LiStructural Biology Program, Van Andel Institute, Grand Rapids, MI, USA. Huilin.Li@vai.org.ORCID http://orcid.org/0000-0001-8085-8928
Michael W W AdamsDepartment of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA. adamsm@uga.edu.ORCID http://orcid.org/0000-0002-9796-5014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern day aerobic respiration in mitochondria involving complex I converts redox energy into chemical energy and likely evolved from a simple anaerobic system now represented by hydrogen gas-evolving hydrogenase (MBH) where protons are the terminal electron acceptor. Here we present the cryo-EM structure of an early ancestor in the evolution of complex I, the elemental sulfur (S

Indexed as

CatalysisCatalytic DomainCryoelectron MicroscopyElectron Transport Complex IHydrogenaseIron-Sulfur ProteinsMitochondrial MembranesModels, MolecularOrigin of LifeOxidation-ReductionOxidoreductasesProton PumpsPyrococcus furiosusSodium-Hydrogen ExchangersSulfurElectron Transport Complex IHydrogenaseIron-Sulfur Proteinsnickel-iron hydrogenaseOxidoreductasesProton PumpsSodium-Hydrogen ExchangersSulfur

Identifiers

PMID33230146
PMCPMC7684303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.