Observational studyIndian journal of ophthalmology2020
Study on change in corneal biomechanics and effect of percent tissue altered in myopic laser-assisted
Observational study in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Corneal biomechanics with CORVIS-ST in post-keratoplasty corneas.Indian journal of ophthalmology · 2026Observational
- Impact of Flap Thickness on Refractive Outcomes and Corneal Biomechanics Following Myopic Femtosecond Laser-Assisted LASIK.Journal of clinical medicine · 2026Article
- Clinical Evaluation of Corneal Biomechanics following Laser Refractive Surgery in Myopic Eyes: A Review of the Literature.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate corneal biomechanical changes and their correlation with the percentage of tissue altered (PTA) in myopic femtosecond (FS)-flap LASIK.
methodsProspective longitudinal observational study of 80 eyes of FS LASIK. Demographic details, LASIK parameters, preoperative and postoperative (day 1, month 1, 3, and 6), UCVA, BCVA, refraction, corneal topography, corneal hysteresis (CH), and a corneal resistance factor (CRF) were noted. Change in CH and CRF and its correlation with PTA were analyzed. Data were analyzed in three subgroups [subgroup 1: PTA 23 to <27%; subgroup 2: 27 to <33%; subgroup 3: 33 to <40%].
resultsFS LASIK for MRSE -3.5D ± 1.6D with mean PTA of 31.6 ± 4.4% (range 23.8-39.8%), showed statistically significant decrease in CH and CRF. Mean CH decreased from a preoperative value of 10.4 ± 1.9 to 8.1 ± 1.1; mean CRF from 10.5 ± 1.6 to 7.5 ± 1.3 at 6-months postoperative period, respectively. Mean preoperative CH decreased by 25%, 24%, 23%, and 21% and mean preoperative CRF decreased by 34%, 28%, 28%, and 28% at postoperative day 1, month 1, 3, and 6 follow-ups. Mean CH and CRF showed a significant negative correlation with PTA (CH: r = - 0.33 [P = <0.0001], CRF: r = -0.34 [P = <0.001]. Subgroup analysis noted greater decrease in CRF and CH in eyes with higher PTA (subgroup 3).
conclusionMyopic FS LASIK causes a decrease in corneal biomechanics with a significant negative correlation with PTA indicating a greater decrease in corneal biomechanics with higher PTA.
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