ArticleIndian journal of ophthalmology2020
Age-related variation in corneal biomechanical parameters in healthy Indians.
Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The Corvis ST analysis of underaged versus adults' healthy eyes with comparable tomography detects softer corneas in children and adolescents as opposed to adults.Scientific reports · 2026Article
- Corneal biomechanics with CORVIS-ST in post-keratoplasty corneas.Indian journal of ophthalmology · 2026Observational
- Progression and regression of keratoconus in an Iranian population.Scientific reports · 2025Article
- Comparison of biomechanical indices measured by ocular response analyzer between children and elderly: a systematic review.International journal of ophthalmology · 2025Review
- Corneal strain influences keratocyte proliferation and migration through upregulation of ALDH3A1 expression.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024Article
- Age-related analysis of corneal biomechanical parameters in healthy Chinese individuals.Scientific reports · 2024Article
- Corneal Biomechanical Changes in Patients with Inherited Retinal Diseases.Clinical ophthalmology (Auckland, N.Z.) · 2024Article
- Effect of ocular biometric factors on corneal biomechanical properties.International ophthalmology · 2023Article
- Corneal Biomechanics Differences Between Chinese and Caucasian Healthy Subjects.Frontiers in medicine · 2022Article
- Corneal stress-strain index in myopic Indian population.Oman journal of ophthalmologyArticle
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3 authors.
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Abstract
purposeTo report age-related variations in corneal biomechanical parameters in healthy Indians.
methodsA retrospective study where healthy Indian individuals aged between 5 and 70 years having undergone corneal biomechanics assessment using Corvis ST between January 2017 and December 2018 and having best corrected visual acuity of 20/20 were enrolled. Subjects with central corneal thickness <500 microns, intra-ocular pressure (IOP) ≥ 22 mmHg, refractive error ≥ 6.00D, history of any systemic and ocular disease, previous ocular surgery, poor scans quality, and subjects with any missing data were also excluded. Corneal biomechanical parameters were noted and compared across different age groups.
resultsTotal of 3125 eyes had undergone the Corvis ST analysis. After applying exclusion criteria, 718 right eyes of 718 patients were included for the analysis and were further divided into different age groups as per each decade (sample size), such as 5-10 (37), 11-20 (113), 21-30 (396), 31-40 (116), 41-50 (39), 50 and above (17). All the subjects were matched for IOP and central corneal thickness (p > 0.05). A total of 19 out of 26 corneal biomechanical parameters were significantly different across age groups (p < 0.05). Vinciguerra screening parameters, such as deformation amplitude ratio max, biomechanically corrected IOP, and stiffness parameter A1 were significantly different across different age groups (p < 0.05).
conclusionCorneal biomechanical parameters are affected by age as cornea becomes progressively stiffer. The information reported here would serve as a reference for future corneal biomechanical researches and would help in differentiating the abnormal eyes from normal healthy eyes.
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