Evidence map›Paper›PMID 33229657›Full record

ReviewIndian journal of ophthalmology2020

Advanced epithelial mapping for refractive surgery.

Pooja Khamar, Kavita Rao, Kareeshma Wadia, Ritika Dalal, Tushar Grover, Francesco Versaci, Krati Gupta

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Deep learning approach for analyzing regional scheimpflug corneal images to assess keratoconus progression.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Observational
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pooja KhamarDepartment of Cataract and Refractive Surgery, Narayana Nethralaya, Bengaluru, India.
Kavita RaoDirector, Cornea, Cataract and Refractive Surgery Services, Aditya Jyot Eye Hospital, Mumbai, India.
Kareeshma WadiaCornea, Cataract and Refractive Surgery Services, Jehan Eye Clinic, Vile Parle West, Mumbai, India.
Ritika DalalRefractive Surgeon and Dry Eye Specialist, Dr Dalal's Clinic, Mumbai, India.
Tushar GroverDirector, Vision Eye Centre & Associate Consultant, Sir Ganga Ram Hospital, New Delhi, India.
Francesco VersaciSenior Engineer, CSO srl, Italy.
Krati GuptaDepartment of Cornea and Refractive Surgery,, Narayana Nethralaya, Bengaluru, India.
Narayana Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the leading challenges in refractive surgery today is the presence of underlying subclinical early-stage keratoconus (KC), which can lead to iatrogenic post laser in situ keratomileusis ectasia. Timely detection of this condition could aid the refractive surgeons in better decision-making. This includes being able to defer refractive surgery in subclinical cases as well as providing treatment for the same in the form of appropriate corneal collagen crosslinking treatments. Corneal topography is considered the gold standard for the diagnosis of corneal ectatic disorders. However, there is a likelihood that topographers are overlooking certain subclinical cases. The corneal epithelium is known to remodel, which may mask underlying stromal irregularities. Imaging and analyzing corneal epithelium and stroma independently will undoubtedly open newer avenues to supplement our understanding of postrefractive surgery outcomes and KC. This review encapsulates the various Optical coherence tomography-based epithelial mapping devices particularly RTVue (Optovue, Fremont, USA) and MS-39 (Costruzione Strumenti Oftalmici, Florence, Italy) in terms of their utility in these conditions. It will help guide the clinician on how including an epithelial mapping in clinical practice can aid in diagnosis, management, and interpretation of outcomes both for refractive surgery as well as KC.

Indexed as

Epithelium, CornealKeratoconusKeratomileusis, Laser In SituCorneal TopographyHumansTomography, Optical CoherenceEpithelial mappingkeratoconuspreferred practicesrefractive surgery

Identifiers

PMID33229657
PMCPMC7856960
OpenAlexW3107900083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.