Evidence map›Paper›PMID 33229627›Full record

ArticleAging2020

DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas.

Tingyu Liang, Xingang Zhou, Peiliang Li, Gan You, Fang Wang, Peng Wang, Enshan Feng

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Pharmacogenomics and personalized medicine · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tingyu LiangDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Xingang ZhouDepartment of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Peiliang LiDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Gan YouDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Fang WangDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Peng WangDepartment of Pathology, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Enshan FengDepartment of Neurosurgery, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Beijing Ditan Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant glioma is the most common form of primary malignant brain cancer. Heterogeneity is the hallmark of glioma. DAZ-interacting zinc finger 3 (DZIP3), acts as an RNA-binding RING-type ubiquitin ligase; however, its function in glioma is yet unclear.

resultsThe

conclusionIn conclusion, the loss of DZIP3 may be involved in the mechanism of angiogenesis in the invasive biological process of glioma. These findings laid an understanding of DZIP3-specific clinical features in glioma.

methodsA total of 325 glioma patients from the Chinese Glioma Genome Atlas (CGGA) RNA-seq cohort comprised the training cohort, while 265 patients from the GSE 16011 array cohort formed the validation cohort. The mRNA expression of

Indexed as

AstrocytomaBrain NeoplasmsGlioblastomaGliomaHumansImmunohistochemistryIsocitrate DehydrogenaseNeoplasm GradingNeovascularization, PathologicOligodendrogliomaPrognosisRNA-Binding ProteinsRNA, MessengerRNA-SeqSurvival RateUbiquitin-Protein LigasesDZIP3 protein, humanIDH1 protein, humanIsocitrate DehydrogenaseRNA-Binding ProteinsRNA, MessengerUbiquitin-Protein LigasesDZIP3gliomaIDH1 wild-typesurvival time

Identifiers

PMID33229627
PMCPMC7803555
OpenAlexW3108880397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.