ArticleProceedings of the National Academy of Sciences of the United States of America2020
Representations of common event structure in medial temporal lobe and frontoparietal cortex support efficient inference.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Article
- Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex.Nature neuroscience · 2026Article
- Increasing representational capacity in the hippocampal-frontoparietal system underlies hierarchical development of temporal memory.Developmental cognitive neuroscience · 2026Review
- Children and adults use distinct neurocognitive mechanisms to support successful memory-based inference.bioRxiv : the preprint server for biology · 2026Article
- Distinct Hippocampal Mechanisms Support Concept Formation and Updating.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements.PLoS biology · 2026Article
- Hippocampal connectivity predicting recognition and categorization abilities.Frontiers in cognition · 2026Article
- Hippocampal-prefrontal orchestration supports higher-order learning for creative ideation.Nature communications · 2025Article
- Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes.Nature communications · 2025Article
- Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Differentiation of Related Events in Hippocampus Supports Memory Reinstatement in Development.Journal of cognitive neuroscience · 2025Article
- Striatal arbitration between choice strategies guides few-shot adaptation.Nature communications · 2025Article
- Neural codes track prior events in a narrative and predict subsequent memory for details.Communications psychology · 2025Article
- Neural mechanisms of relational learning and fast knowledge reassembly in plastic neural networks.Nature neuroscience · 2025Article
- Abstract rule generalization for composing novel meaning recruits a frontoparietal control network.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The representation of abstract goals in working memory is supported by task-congruent neural geometry.PLoS biology · 2024Article
- Article
- Neural Activity Differentiates Novel and Learned Event Boundaries.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- Agency effects on the binding of event elements in episodic memory.Quarterly journal of experimental psychology (2006) · 2024Article
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3 authors.
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Abstract
Prior work has shown that the brain represents memories within a cognitive map that supports inference about connections between individual related events. Real-world adaptive behavior is also supported by recognizing common structure among numerous distinct contexts; for example, based on prior experience with restaurants, when visiting a new restaurant one can expect to first get a table, then order, eat, and finally pay the bill. We used a neurocomputational approach to examine how the brain extracts and uses abstract representations of common structure to support novel decisions. Participants learned image pairs (AB, BC) drawn from distinct triads (ABC) that shared the same internal structure and were then tested on their ability to infer indirect (AC) associations. We found that hippocampal and frontoparietal regions formed abstract representations that coded cross-triad relationships with a common geometric structure. Critically, such common representational geometries were formed despite the lack of explicit reinforcement to do so. Furthermore, we found that representations in parahippocampal cortex are hierarchical, reflecting both cross-triad relationships and distinctions between triads. We propose that representations with common geometric structure provide a vector space that codes inferred item relationships with a direction vector that is consistent across triads, thus supporting faster inference. Using computational modeling of response time data, we found evidence for dissociable vector-based retrieval and pattern-completion processes that contribute to successful inference. Moreover, we found evidence that these processes are mediated by distinct regions, with pattern completion supported by hippocampus and vector-based retrieval supported by parahippocampal cortex and lateral parietal cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.