Evidence map›Paper›PMID 33229505›Full record

ReviewESMO open2020

Prevention of venous thromboembolism in ambulatory patients with cancer.

Alok A Khorana, Alexander T Cohen, Marc Carrier, Guy Meyer, Ingrid Pabinger, Petr Kavan, PhilipS Wells

Open access · goldAbstract readReview
In one paragraph

Review in ESMO open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Implementation failure: thromboprophylaxis in ambulatory patients with cancer.Hematology. American Society of Hematology. Education Program · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Assessing the risk of venous thromboembolism (VTE) in ambulatory patients with cancer: Rationale and implementation of a pharmacist-led VTE risk assessment program in an ambulatory cancer centre.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2021
    Article
  13. The Application of the ThroLy Risk Assessment Model to Predict Venous Thromboembolism in Patients with Diffuse Large B-Cell Lymphoma.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Alok A KhoranaDepartment of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, United States. Electronic address: khorana@ccf.org.
Alexander T CohenDepartment of Haematological Medicine, Guys and St Thomas' Hospitals, King's College London, London, United Kingdom.
Marc CarrierDepartment of Medicine, University of Ottawa, Ottawa Hospital Research Institute at the University of Ottawa, Ottawa, Ontario, Canada.
Guy MeyerHôpital Européen Georges-Pompidou AP-HP, Université Paris Descartes, Paris, France.
Ingrid PabingerComprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.
Petr KavanDepartment of Oncology, Jewish General Hospital, McGill University, Montreal, Québec, Canada.
PhilipS WellsDepartment of Medicine, University of Ottawa, Ottawa Hospital Research Institute at the University of Ottawa, Ottawa, Ontario, Canada.
University of Ottawa · CACleveland Clinic · USComprehensive Cancer Center Vienna · ATJewish General Hospital · CASt Thomas' Hospital · GBUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with cancer are at high risk of venous thromboembolic events, and this risk can be further increased in patients with certain cancer types and by cancer treatments. Guidelines on the prevention of cancer-associated thrombosis (CAT) recommend thromboprophylaxis for hospitalised patients; however, this is not routinely recommended for ambulatory patients receiving chemotherapy and is limited to specified high-risk patients. Identification of the ambulatory patients at risk of CAT who would most benefit from anticoagulant therapy is therefore critical to reduce the incidence of this complication. For patients receiving thromboprophylaxis for CAT, treatment options include low molecular weight heparin, acetylsalicylic acid, warfarin or direct oral anticoagulants (apixaban or rivaroxaban), dependent on the cancer type and cancer treatment regimen. This review discusses emerging clinical trial data and their potential clinical impact.

Indexed as

NeoplasmsVenous ThromboembolismAnticoagulantsHeparin, Low-Molecular-WeightHumansRivaroxabanWarfarinAnticoagulantsHeparin, Low-Molecular-WeightRivaroxabanWarfarinanticoagulantcancer-associated thrombosisdirect oral anticoagulantlow molecular weight heparinthromboprophylaxisvenous thromboembolism

Identifiers

PMID33229505
PMCPMC7684816
OpenAlexW3106792472

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.