Evidence map›Paper›PMID 33229435›Full record

ArticleThe Journal of biological chemistry

Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.

Renuka Kadirvelraj, Jeong-Yeh Yang, Hyun W Kim, Justin H Sanders, Kelley W Moremen, Zachary A Wood

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter forJournal of the American Chemical Society · 2026
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  4. Review
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  6. Article
  7. Iterative Bump-and-hole engineering creates a bioorthogonal reporter forbioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Protein N -Glycans in Healthy and Sclerotic Glomeruli in Diabetic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2024
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Cells · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Renuka KadirvelrajDepartment of Biochemistry & Molecular Biology, University of Georgia, Athens, Georgia, USA.
Jeong-Yeh YangComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA.
Hyun W KimDepartment of Biochemistry & Molecular Biology, University of Georgia, Athens, Georgia, USA.
Justin H SandersDepartment of Biochemistry & Molecular Biology, University of Georgia, Athens, Georgia, USA.
Kelley W MoremenDepartment of Biochemistry & Molecular Biology, University of Georgia, Athens, Georgia, USA; Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA. Electronic address: moremen@uga.edu.
Zachary A WoodDepartment of Biochemistry & Molecular Biology, University of Georgia, Athens, Georgia, USA. Electronic address: zaw@uga.edu.
University of Georgia · US

Funding

TR&D3. Approaches to Proteoglycan Function at Biochemical and Cellular LevelsP41GM103390 · NIGMS · UNIVERSITY OF GEORGIA · PI MOREMEN, KELLEY W. · 2012 to 2019
$14.5M
Recombinant Production of Glycosylation Enzymes for Biochem/Structural StudiesP01GM107012 · NIGMS · UNIVERSITY OF GEORGIA · PI PRESTEGARD, JAMES H. · 2013 to 2017
$7.5M
Origin of N-Glycan Site-Specific HeterogeneityR01GM130915 · NIGMS · UNIVERSITY OF GEORGIA · PI KANNAN, NATARAJAN, MOREMEN, KELLEY W. · 2019 to 2022
$3.4M
NIGMS NIH HHS P01 GM107012NIGMS NIH HHS P41 GM103390NIGMS NIH HHS R01 GM130915
6 · The paper itself

Abstract

Poly-N-acetyl-lactosamine (poly-LacNAc) structures are composed of repeating [-Galβ(1,4)-GlcNAcβ(1,3)-]

Indexed as

Amino SugarsBinding SitesCatalysisChromatography, GelGlycosyltransferasesHEK293 CellsHumansN-AcetylglucosaminyltransferasesSubstrate SpecificityAmino SugarsB3GNT2 protein, humanGlycosyltransferasesN-AcetylglucosaminyltransferasesN-acetyllactosamineenzyme mechanismglycosyltransferasesubstrate recognition

Identifiers

PMID33229435
PMCPMC7948508
OpenAlexW3109479219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.