Evidence map›Paper›PMID 33229199›Full record

SynthesisNutrition, metabolism, and cardiovascular diseases : NMCD2021

Prevalence and clinical outcomes of cardiac injury in patients with COVID-19: A systematic review and meta-analysis.

Zhen Huang, Pan Huang, Binbin Du, Lingyao Kong, Wenyuan Zhang, Yanzhou Zhang, Jianzeng Dong

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia.Journal of cardiovascular development and disease · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection.Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Review
  14. Article
  15. Distinct Coagulopathy With Myocardial Injury and Pulmonary Embolism in COVID-19.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhen HuangDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Pan HuangCollege of Nursing, Gannan Medical University, Ganzhou, Jiangxi province, China.
Binbin DuDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Lingyao KongDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Wenyuan ZhangDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Yanzhou ZhangDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China.
Jianzeng DongDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. Electronic address: jzdong@zzu.edu.cn.
First Affiliated Hospital of Zhengzhou University · CNGannan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsEmerging data have linked the presence of cardiac injury with a worse prognosis in novel coronavirus disease 2019 (COVID-19) patients. However, available data cannot clearly characterize the correlation between cardiac injury and COVID-19. Thus, we conducted a meta-analysis of recent studies to 1) explore the prevalence of cardiac injury in different types of COVID-19 patients and 2) evaluate the association between cardiac injury and worse prognosis (severe disease, admission to ICU, and mortality) in patients with COVID-19. METHODS AND

resultsLiterature search was conducted through PubMed, the Cochrane Library, Embase, and MedRxiv databases. A meta-analysis was performed with Stata 14.0. A fixed-effects model was used if the I

conclusionsThe prevalence of cardiac injury was greatly increased in COVID-19 patients, particularly in patients with severe disease and non-survivors. COVID-19 patients with cardiac injury are more likely to be associated with poor outcomes, severity of disease, admission to ICU, and mortality.

Indexed as

AdultAgedAged, 80 and overCOVID-19FemaleHeart DiseasesHospitalizationHumansIntensive Care UnitsMaleMiddle AgedPrevalencePrognosisSARS-CoV-2Severity of Illness IndexCardiac injuryCOVID-19OutcomePrevalenceSARS-CoV-2

Identifiers

PMID33229199
PMCPMC7485447
OpenAlexW3086862690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.