Evidence map›Paper›PMID 33228744›Full record

Trial reportTrials2020

Parents' understanding and motivation to take part in a randomized controlled trial in the field of adolescent mental health: a qualitative study.

Sally O'Keeffe, Katharina Weitkamp, Danny Isaacs, Mary Target, Virginia Eatough, Nick Midgley

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Parents' and children's experiences of participating in a randomized controlled clinical trial: AIDIT-QS.International journal of qualitative studies on health and well-being · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Sally O'KeeffeChild Attachment and Psychological Therapies Research Unit (ChAPTRe), Anna Freud National Centre for Children and Families, 4-8 Rodney Street, London, N1 9JH, UK.
Katharina WeitkampUniversity of Zurich, Zurich, Switzerland.
Danny IsaacsAdolescent and Young Adult Service, Tavistock and Portman NHS Foundation Trust, London, UK.
Mary TargetResearch Department of Clinical, Educational and Health Psychology, University College London, London, UK.
Virginia EatoughDepartment of Psychological Sciences, Birkbeck College, University of London, London, UK.
Nick MidgleyChild Attachment and Psychological Therapies Research Unit (ChAPTRe), Anna Freud National Centre for Children and Families, 4-8 Rodney Street, London, N1 9JH, UK. nick.midgley@annafreud.org.ORCID http://orcid.org/0000-0002-6263-5058
Anna Freud Centre · GBBirkbeck, University of London · GBCity, University of London · GBThe Tavistock and Portman NHS Foundation Trust · GBUniversity College London · GBUniversity of Zurich · CH

Funding

Monument Trust MON5229
6 · The paper itself

Abstract

backgroundLittle is known about why parents agree to take part in randomized controlled trials for adolescent mental health. This study aimed to investigate parents' perspectives on participating in a trial for psychological treatment of depression. The study explored parents' motivations, understanding of the trial and perspectives on the acceptability of the trial.

methodsSixty-five parents took part in this qualitative study. Their adolescent children had been randomly allocated to one of three active psychological treatments for depression as part of the IMPACT trial and were interviewed about their experiences of participating in the study. Semi-structured interviews were analysed using framework analysis.

resultsFor seven of the sixty-five parents, their experience of taking part in the trial was not covered in their interview so they were excluded from the analysis. The analysis was therefore based on the data from the parents of 58 adolescents taking part in the trial. The most commonly cited motivation for taking part in the study reported by parents was a desire to help others going through similar difficulties. Parents generally reported finding trial participation acceptable, although there were aspects that some reported finding less acceptable, including randomization and the burden of research assessments. Others spoke positively about the experience of trial participation and found it enjoyable or even therapeutic. Importantly, some did not appear to have a good understanding of the trial design, including randomization and treatment allocation.

conclusionsThis study indicates that trial participation can be a positive experience for parents, yet it raises concerns about how trialists can ensure that consent is fully informed, given that some parents appeared to have a poor understanding of the trial. Future studies should seek to explore how communication with trial participants can be improved, to ensure that trial participation is fully informed. Patient and public involvement will be crucial in ensuring this communication is accessible to stakeholders.

trial registrationISRCTN registry ISRCTN83033550 . Registered on 15 October 2009.

Indexed as

Mental HealthMotivationAdolescentChildCommunicationHumansParentsQualitative ResearchAdolescenceDepressionParents’ perspectivesQualitativeRandomized controlled trialTrial participation

Identifiers

PMID33228744
PMCPMC7684724
OpenAlexW3106951843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.