Evidence map›Paper›PMID 33228582›Full record

ArticleBMC pregnancy and childbirth2020

Nationwide population-based cohort study of adverse obstetric outcomes in pregnancies with myoma or following myomectomy: retrospective cohort study.

Se Jin Lee, Hyun Sun Ko, Sunghun Na, Jin Young Bae, Won Joon Seong, Jong Woon Kim, Jaeeun Shin, Hae Joong Cho, Gyu Yeon Choi, Jinsil Kim and 2 more

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Understanding the role of vitamin D in osteosarcoma: A narrative review.Medical oncology (Northwood, London, England) · 2025
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  11. Cystic Adenomyoma in Pregnancy: A Case Report.International journal of women's health · 2024
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Se Jin LeeDepartment of Obstetrics and Gynecology, Kangwon National University, School of Medicine, Chuncheon, South Korea.
Hyun Sun KoDepartment of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.
Sunghun NaDepartment of Obstetrics and Gynecology, Kangwon National University, School of Medicine, Chuncheon, South Korea.
Jin Young BaeDepartment of Obstetrics and Gynecology, School of Medicine, Catholic University of Daegu, Daegu, South Korea.
Won Joon SeongDepartment of Obstetrics and Gynecology, Kyungpook National University, School of Medicine, Daegu, South Korea.
Jong Woon KimDepartment of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, South Korea.
Jaeeun ShinBucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Bucheon, South Korea.
Hae Joong ChoDepartment of Obstetrics and Gynecology, College of Medicine, Wonkwang University, Iksan, South Korea.
Gyu Yeon ChoiDepartment of Obstetrics and Gynecology, Soonchunhyang University Seoul Hospital, Seoul, South Korea.
Jinsil KimDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea.
Geum Joon ChoDepartment of Obstetrics and Gynecology, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea. geumjoon@korea.ac.kr.
In Yang ParkDepartment of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea. ooooobbbbb@catholic.ac.kr.

Funding

Korean society of Maternal Fetal Medicine Research Fund KSMFM-2019-001
6 · The paper itself

Abstract

backgroundOur objective was to evaluate risks of adverse obstetric outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy.

methodsWe analyzed the national health insurance database, which covers almost the entire Korean population, between 2004 and 2015. The risks of adverse pregnancy outcomes in pregnancies with myoma(s) or in pregnancies following myomectomy, compared to those in women without a diagnosed myoma, were analyzed in multivariate logistic regression analysis.

resultsDuring the study period, 38,402 women with diagnosed myoma(s), 9890 women with a history of myomectomy, and 740,675 women without a diagnosed myoma gave birth. Women with a history of diagnosed myoma(s) and women with a history of myomectomy had significantly higher risks of cesarean section (aOR 1.13, 95% CI 1.1-1.16 and aOR 7.46, 95% CI 6.97-7.98, respectively) and placenta previa (aOR 1.41, 95% CI 1.29-1.54 and aOR 1.58, 95% CI 1.35-1.83, respectively), compared to women without a diagnosed myoma. And the risk of uterine rupture was significantly higher in women with previous myomectomy (aOR 12.78, 95% CI 6.5-25.13), compared to women without a diagnosed myoma, which was much increased (aOR 41.35, 95% CI 16.18-105.69) in nulliparous women. The incidence of uterine rupture was the highest at delivery within one year after myomectomy and decreased over time after myomectomy.

conclusionsWomen with a history of myomectomy had significantly higher risks of cesarean section and placenta previa compared to women without a diagnosed myoma.

Indexed as

AdultCesarean SectionFemaleHumansLeiomyomaLogistic ModelsMultivariate AnalysisPlacenta PreviaPregnancyPregnancy ComplicationsPregnancy OutcomeRepublic of KoreaRetrospective StudiesUterine MyomectomyUterine NeoplasmsUterine RuptureMyomaMyomectomyPregnancy outcomeUterine rupture

Identifiers

PMID33228582
PMCPMC7685654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.