Evidence map›Paper›PMID 33228554›Full record

ArticleBMC cardiovascular disorders2020

Comparison of QT dispersion in patients with ST elevation acute myocardial infarction (STEMI) before and after treatment by streptokinase versus primary percutaneous coronary intervention (PCI).

Abbas Valizadeh, Sahar Soltanabadi, Saeed Koushafar, Maryam Rezaee, Reza Jahankhah

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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  8. Effect of pulmonary embolism location on electrocardiological parameters.Revista da Associacao Medica Brasileira (1992) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Abbas ValizadehDepartment of Cardiology, Fasa University of Medical Sciences, Fasa, Iran.
Sahar SoltanabadiStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran. saharsoltany@gmail.com.ORCID 0000-0002-3628-9438
Saeed KoushafarStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran.
Maryam RezaeeDermatology Department, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Reza JahankhahDepartment of Radiology, Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Fasa University of Medical Sciences · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQT dispersion (QTD) represents inhomogeneous ventricular repolarization such that an increased QTD may predispose the heart to malignant ventricular arrhythmias (VAs). This study was conducted to compare QTD in patients with ST-elevation myocardial infarction (STEMI) before and after treatment by streptokinase (SK) versus primary percutaneous coronary intervention (PCI).

methodsThe present case-control study was conducted on 185 STEMI patients who received SK (115 cases) or underwent primary PCI (70 cases). QTD and QT corrected dispersion before and 24 h after treatment. Likewise, they were also found to correct fatal arrhythmias (VT and VF) during the first 24 h after admission, and ejection fraction (EF) 24 h after treatment was evaluated.

resultsQTD decreased in the primary PCI group, though no significant difference was seen between the two studied groups (P > 0.05). A significant increase was detected in the EF mean values for the primary PCI-treated patients (P = 0.022). Moreover, there was a significant reduction in QTD of patients with fatal arrhythmias in the primary PCI group (P = 0.022).

conclusionAn overall QTD reduction in the primary PCI group and a significant decrease in QTD of patients with fatal arrhythmias in the primary PCI group show that this treatment strategy is more efficient than thrombolytic therapy. As an important indicator of proper myocardial function, EF can independently predict improved myocardial function in the primary PCI group.

Indexed as

Action PotentialsHeart RatePercutaneous Coronary InterventionThrombolytic TherapyAgedCase-Control StudiesFemaleFibrinolytic AgentsHumansMaleMiddle AgedRisk FactorsST Elevation Myocardial InfarctionStreptokinaseTachycardia, VentricularTime FactorsFibrinolytic AgentsStreptokinaseMyocardial infarctionPrimary PCIQT dispersionStreptokinase

Identifiers

PMID33228554
PMCPMC7685573
OpenAlexW3107601561

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.