Evidence map›Paper›PMID 33228547›Full record

ArticleBMC nephrology2020

Survival and analysis of predictors of mortality in patients undergoing replacement renal therapy: a 20-year cohort.

Emily de Souza Ferreira, Tiago Ricardo Moreira, Rodrigo Gomes da Silva, Glauce Dias da Costa, Luciana Saraiva da Silva, Samantha Bicalho de Oliveira Cavalier, Beatriz Oliveira Silva, Heloísa Helena Dias, Luiza Delazari Borges, Juliana Costa Machado and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Peritoneal dialysis versus haemodialysis for people commencing dialysis.The Cochrane database of systematic reviews · 2024
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  7. The humanistic burden of focal segmental glomerulosclerosis on patients and care-partners in the United States.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  9. Review
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  11. One-year Survival of End-Stage Kidney Disease Patients Undergoing Hemodialysis in Indonesia.International journal of nephrology and renovascular disease · 2025
    Article
  12. Article
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  15. Article
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  17. Article
  18. Prognostication After Dialysis Withdrawal.Kidney international reports · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Emily de Souza FerreiraDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil. emilynutufv@gmail.com.ORCID 0000-0003-4451-0611
Tiago Ricardo MoreiraDepartment of Medicine and Nursing, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Rodrigo Gomes da SilvaNephrology Service, Hospital São João Batista, Viçosa, Minas Gerais, Brazil.
Glauce Dias da CostaDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Luciana Saraiva da SilvaDepartment of Nutrition, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.
Samantha Bicalho de Oliveira CavalierDepartment of Medicine and Nursing, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Beatriz Oliveira SilvaDepartment of Medicine and Nursing, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Heloísa Helena DiasDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Luiza Delazari BorgesDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Juliana Costa MachadoDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Rosângela Minardi Mitre CottaDepartment of Nutrition and Health, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.
Universidade Federal de Viçosa · BRHospital São Vicente · BRUniversidade Federal de Uberlândia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundoptimal management of end-stage renal disease (ESRD) in hemodialysis (HD) patients should be more studied because it is a serious risk factor for mortality, being considered an unquestionable global priority.

methodswe performed a retrospective cohort study from the Nephrology Service in Brazil evaluating the survival of patients with ESRD in HD during 20 years. Kaplan-Meier method with the Log-Rank and Cox's proportional hazards model explored the association between survival time and demographic factors, quality of treatment and laboratory values.

resultsData from 422 patients were included. The mean survival time was 6.79 ± 0.37. The overall survival rates at first year was 82,3%. The survival time correlated significantly with clinical prognostic factors. Prognostic analyses with the Cox proportional hazards regression model and Kaplan-Meier survival curves further identified that leukocyte count (HR = 2.665, 95% CI: 1.39-5.12), serum iron (HR = 8.396, 95% CI: 2.02-34.96), serum calcium (HR = 4.102, 95% CI: 1.35-12.46) and serum protein (HR = 4.630, 95% CI: 2.07-10.34) as an independent risk factor for the prognosis of survival time, while patients with chronic obstructive pyelonephritis (HR = 0.085, 95% CI: 0.01-0.74), high ferritin values (HR = 0.392, 95% CI: 0.19-0.80), serum phosphorus (HR = 0.290, 95% CI: 0.19-0.61) and serum albumin (HR = 0.230, 95% CI: 0.10-0.54) were less risk to die.

conclusionsurvival remains low in the early years of ESRD treatment. The present study identified that elevated values of ferritin, serum calcium, phosphorus, albumin, leukocyte, serum protein and serum iron values as a useful prognostic factor for the survival time.

Indexed as

Renal Replacement TherapyAgedAged, 80 and overBiomarkersBlood ProteinsCalciumFemaleHumansIronKaplan-Meier EstimateKidney Failure, ChronicLeukocyte CountMaleMiddle AgedPhosphorusPrognosisBiomarkersBlood ProteinsCalciumIronPhosphorusSerum AlbuminChronic kidney disease; biochemical parameterEnd-stage renal diseaseHemodialysisRenal replacement therapy

Identifiers

PMID33228547
PMCPMC7685664
OpenAlexW3108607500

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.