Evidence map›Paper›PMID 33228541›Full record

ArticleBMC geriatrics2020

Measuring global functioning in older adults with cognitive impairments using the Rasch model.

Rocco Palumbo, Alberto Di Domenico, Federica Piras, Salvatore Bazzano, Mario Zerilli, Fabio Lorico, Erika Borella

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Article in BMC geriatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rocco PalumboDepartment of Psychological, Health and Territorial Sciences, University of Chieti, Via dei Vestini 31, 66100, Chieti, Italy. rocco.palumbo@unich.it.ORCID 0000-0002-2385-5840
Alberto Di DomenicoDepartment of Psychological, Health and Territorial Sciences, University of Chieti, Via dei Vestini 31, 66100, Chieti, Italy.
Federica PirasIRCCS Santa Lucia Foundation, Neuropsychiatry Laboratory, Clinical and Behavioral Neurology Department, Rome, Italy.
Salvatore BazzanoCentro Decadimento Cognitivo Asl7 di Bassano del Grappa, Bassano del Grappa, Italy.
Mario ZerilliCentro Decadimento Cognitivo Asl7 di Bassano del Grappa, Bassano del Grappa, Italy.
Fabio LoricoCentro Decadimento Cognitivo Asl7 di Bassano del Grappa, Bassano del Grappa, Italy.
Erika BorellaDepartment of General Psychology, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCognitive and functional measures are often measured and interpreted separately during the clinical evaluation of patients with cognitive impairment. This can sometimes lead to a challenging interpretation when measures do not show concordance, especially after a clinical intervention. In this study, the development and evaluation of a new approach, using the Rasch model, that combines cognitive and functional measures in one single and more powerful measure (compared to stand-alone tests) to assess global functioning in older adults with cognitive impairment (including dementia) was presented.

methodsClinical data from 265 older adults' subjects diagnosed with mild cognitive impairment, or dementia, included: The Mini-mental state examination (MMSE), the Esame Neuropsicologico Breve (ENB) - a neuropsychological battery used in Italy-, the Activities of Daily Living (ADL), and the Instrumental Activities of Daily Living (IADL) questionnaires.

resultsPatients with severe cognitive impairment showed lower global functioning score compared to patients with moderate impairment. Receiver Operating Characteristic (ROC) curve analyses were performed to determine sensitivity and specificity of the global functioning score resulting from the combined measure. Results showed that the global functioning score discriminates better between patients with severe and moderate cognitive impairment compared to the ENB, ADL, and IADL when considered separately.

conclusionsThe Rasch model was able to combine cognitive and functional measures into a single score (global functioning score). All together, these results suggest that the diverse cognitive and functional measures can be considered part of one single dimension (global functioning) and that this dimension can be measured as a single construct and score. This study offers an alternative perspective for future development of instruments that would help clinicians in measuring global functioning in older adults' patients at different stages of cognitive impairments and different baseline level of performance.

Indexed as

Activities of Daily LivingCognitive DysfunctionAgedHumansItalyMental Status and Dementia TestsNeuropsychological TestsSensitivity and SpecificityActivities of daily livingCognitive impairmentGlobal functioningMCIRasch model

Identifiers

PMID33228541
PMCPMC7685614

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