Evidence map›Paper›PMID 33228531›Full record

ArticleBMC genomics2020

GCViT: a method for interactive, genome-wide visualization of resequencing and SNP array data.

Andrew P Wilkey, Anne V Brown, Steven B Cannon, Ethalinda K S Cannon

Abstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew P WilkeyORISE Fellow, USDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA, 50011, USA.
Anne V BrownUSDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA, 50011, USA.
Steven B CannonUSDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA, 50011, USA.
Ethalinda K S CannonUSDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, IA, 50011, USA. ethy.cannon@usda.gov.ORCID http://orcid.org/0000-0002-0678-8754

Funding

Agricultural Research Service 5030-21000-069-00DNational Science Foundation 1444806
6 · The paper itself

Abstract

backgroundLarge genotyping datasets have become commonplace due to efficient, cheap methods for SNP identification. Typical genotyping datasets may have thousands to millions of data points per accession, across tens to thousands of accessions. There is a need for tools to help rapidly explore such datasets, to assess characteristics such as overall differences between accessions and regional anomalies across the genome.

resultsWe present GCViT (Genotype Comparison Visualization Tool), for visualizing and exploring large genotyping datasets. GCViT can be used to identify introgressions, conserved or divergent genomic regions, pedigrees, and other features for more detailed exploration. The program can be used online or as a local instance for whole genome visualization of resequencing or SNP array data. The program performs comparisons of variants among user-selected accessions to identify allele differences and similarities between accessions and a user-selected reference, providing visualizations through histogram, heatmap, or haplotype views. The resulting analyses and images can be exported in various formats.

conclusionsGCViT provides methods for interactively visualizing SNP data on a whole genome scale, and can produce publication-ready figures. It can be used in online or local installations. GCViT enables users to confirm or identify genomics regions of interest associated with particular traits. GCViT is freely available at https://github.com/LegumeFederation/gcvit . The 1.0 version described here is available at https://doi.org/10.5281/zenodo.4008713 .

Indexed as

GenomeGenomicsSoftwareGenotypeHaplotypesPolymorphism, Single NucleotideCViTGCViTGenotypeResequencingSNPUIVisualizationWeb service

Identifiers

PMID33228531
PMCPMC7686774

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.