Evidence map›Paper›PMID 33228525›Full record

ArticleBMC neuroscience2020

Autistic traits are associated with the functional connectivity of between-but not within-attention systems in the general population.

Sayaka Yoshimura, Kei Kobayashi, Tsukasa Ueno, Takashi Miyagi, Naoya Oishi, Toshiya Murai, Hironobu Fujiwara

Abstract read
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In one paragraph

Article in BMC neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sayaka YoshimuraFaculty of Human Health Science, Graduate School of Medicine, Kyoto University, 53 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan. yoshimurasayaka@gmail.com.ORCID 0000-0003-4273-8575
Kei KobayashiDepartment of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Tsukasa UenoDepartment of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Takashi MiyagiDepartment of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Naoya OishiMedical Innovation Center, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Toshiya MuraiDepartment of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.
Hironobu FujiwaraDepartment of Neuropsychiatry, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-Ku, Kyoto, 606-8507, Japan.

Funding

Grant-in-Aid for Scientific Research 16K01790Grant-in-Aid for Scientific Research on Innovative Areas 16H06395Grant-in-Aid for Scientific Research on Innovative Areas 16H06397Grant-in-Aid for Scientific Research on Innovative Areas 16H06402Impulsing Paradigm Change through Disruptive Technologies Program 2015-PM11-08-01
6 · The paper itself

Abstract

backgroundPrevious studies have demonstrated that individuals with autism spectrum disorder (ASD) exhibit dysfunction in the three attention systems (i.e., alerting, orienting, and executive control) as well as atypical relationships among these systems. Additionally, other studies have reported that individuals with subclinical but high levels of autistic traits show similar attentional tendencies to those observed in ASD. Based on these findings, it was hypothesized that autistic traits would affect the functions and relationships of the three attention systems in a general population. Resting-state functional magnetic resonance imaging (fMRI) was performed in 119 healthy adults to investigate relationships between autistic traits and within- and between-system functional connectivity (FC) among the three attention systems. Twenty-six regions of interest that were defined as components of the three attention systems by a previous task-based fMRI study were examined in terms of within- and between-system FC. We assessed autistic traits using the Autism-Spectrum Quotient.

resultsCorrelational analyses revealed that autistic traits were significantly correlated with between-system FC, but not with within-system FC.

conclusionsOur results imply that a high autistic trait level, even when subclinical, is associated with the way the three attention systems interact.

Indexed as

AttentionAdultAutism Spectrum DisorderBrain MappingFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNerve NetNeural PathwaysNeuropsychological TestsYoung AdultAttentionAttention networkAutistic traitsFunctional connectivityResting-state functional magnetic resonance imaging

Identifiers

PMID33228525
PMCPMC7686764

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.