Evidence map›Paper›PMID 33228254›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Afefah Ismail, Julie Wulf Christensen, Martin Krakauer, Susanne Bonnichsen Søndergaard, Bo Zerahn, Birte Nygaard, Finn Noe Bennedbæk, Bent Kristensen, Lars Thorbjørn Jensen

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Head-to-head comparison of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Locating hyperfunctioning parathyroid glands usingEuropean journal of hybrid imaging · 2021
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Afefah IsmailDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Julie Wulf ChristensenDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.ORCID 0000-0003-2680-0121
Martin KrakauerDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Susanne Bonnichsen SøndergaardDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Bo ZerahnDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Birte NygaardDepartment of Medicine, Division of Endocrinology, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.ORCID 0000-0002-9540-4950
Finn Noe BennedbækDepartment of Medicine, Division of Endocrinology, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Bent KristensenDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.
Lars Thorbjørn JensenDepartment of Nuclear Medicine, Herlev and Gentofte Hospital, 2730 Herlev, Denmark.ORCID 0000-0003-1846-4498
Gentofte Hospital · DK

Funding

The Scientific Committee of Herlev University Hospital x
6 · The paper itself

Abstract

backgroundIn patients with primary hyperparathyroidism (PHPT) locating hyperfunctioning glands (HPGs) is crucial when planning minimally invasive surgery. Dual-isotope subtraction scintigraphy with

methodsSixty patients with newly diagnosed PHPT participated and were scanned using both methods prior to parathyroidectomy. We investigated whether sensitivities of Method A and Method B are similar in a method-to-method comparison when using surgical findings as the true location.

resultsAt the patient level, sensitivities were (A) 0.98 (95% CI: 0.90-1.00) and (B) 1.00 (95% CI: 0.93-1.00). At the gland level, sensitivities were (A) 0.88 (95% CI: 0.78-0.94) and (B) 0.87 (95% CI: 0.76-0.92). With a non-inferiority margin of ∆ = -0.1, we found a 1-sided

conclusionOur methods comparison study found that sensitivity of Method B was not inferior to Method A. We suggest that

Indexed as

Choline PETclinical trialmethod comparisonMIBI-subtraction SPECTnon-inferiorityprimary hyperparathyroidismprospective cohort

Identifiers

PMID33228254
PMCPMC7699496
OpenAlexW3103890407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.