Evidence map›Paper›PMID 33228246›Full record

ArticleBiomedicines2020

ACTN4 Mediates SEPT14 Mutation-Induced Sperm Head Defects.

Yu-Hua Lin, Chia-Yen Huang, Chih-Chun Ke, Ya-Yun Wang, Tsung-Hsuan Lai, Hsuan-Che Liu, Wei-Chi Ku, Chying-Chyuan Chan, Ying-Hung Lin

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Genetic etiological spectrum of sperm morphological abnormalities.Journal of assisted reproduction and genetics · 2024
    Review
  3. Article
  4. Article
  5. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yu-Hua LinDepartment of Chemistry, Fu Jen Catholic University, New Taipei City 242, Taiwan.ORCID 0000-0002-6284-4968
Chia-Yen HuangDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan.ORCID 0000-0002-4367-1846
Chih-Chun KePhD Program in Nutrition & Food Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Ya-Yun WangGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Tsung-Hsuan LaiSchool of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Hsuan-Che LiuGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Wei-Chi KuSchool of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Chying-Chyuan ChanDepartment of Obstetrics and Gynecology, Taipei City Hospital, Renai Branch, Taipei 106, Taiwan.
Ying-Hung LinGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.ORCID 0000-0002-1574-1579
Fu Jen Catholic University · TWTaipei City Hospital · TW

Funding

Cardinal Tien Hospital CTH-108A-2A19Cathay General Hospital 106-CGH-FJU-02Ministry of Science and Technology of Taiwan MOST 106-2320-B-030-003-MY3; MOST 109-2320-B-030-002-
6 · The paper itself

Abstract

Septins (SEPTs) are highly conserved GTP-binding proteins and the fourth component of the cytoskeleton. Polymerized SEPTs participate in the modulation of various cellular processes, such as cytokinesis, cell polarity, and membrane dynamics, through their interactions with microtubules, actin, and other cellular components. The main objective of this study was to dissect the molecular pathological mechanism of

Indexed as

ACTN4male infertilitySEPT14septinteratozoospermia

Identifiers

PMID33228246
PMCPMC7699536
OpenAlexW3102041356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.