Evidence map›Paper›PMID 33228210›Full record

ArticleViruses2020

Fatal Interstitial Pneumonia Associated with Bovine Coronavirus in Cows from Southern Italy.

Maria Grazia Amoroso, Giuseppe Lucifora, Barbara Degli Uberti, Francesco Serra, Giovanna De Luca, Giorgia Borriello, Alessandro De Domenico, Sergio Brandi, Maria Concetta Cuomo, Francesca Bove and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  9. Development of a multiplexed Luminex assay for simultaneous detection of enteric viruses in cattle.Veterinary research forum : an international quarterly journal · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Maria Grazia AmorosoUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.ORCID 0000-0002-8663-7445
Giuseppe LuciforaSection of Vibo Valentia, Experimental Zooprophylactic Institute of Southern Italy, Contrada Piano di Bruno, 89852 Mileto, Italy.
Barbara Degli UbertiUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Francesco SerraUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Giovanna De LucaUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Giorgia BorrielloDepartment of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Alessandro De DomenicoFreelance Veterinary, Ordine dei Veterinari di Vibo Valentia, 89900 Vibo Valentia, Italy.
Sergio BrandiUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Maria Concetta CuomoDepartment of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Francesca BoveDepartment of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Marita Georgia RiccardiDepartment of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Giorgio GalieroDepartment of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Giovanna FuscoUnit of Virology, Department of Animal Health, Experimental Zooprophylactic Institute of Southern Italy, Via Salute 2, 80055 Portici, Italy.
Ministero della Salute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An outbreak of winter dysentery, complicated by severe respiratory syndrome, occurred in January 2020 in a high production dairy cow herd located in a hilly area of the Calabria region. Of the 52 animals belonging to the farm, 5 (9.6%) died with severe respiratory distress, death occurring 3-4 days after the appearance of the respiratory signs (caught and gasping breath). Microbiological analysis revealed absence of pathogenic bacteria whilst Real-time PCR identified the presence of RNA from Bovine Coronavirus (BCoV) in several organs: lungs, small intestine (jejunum), mediastinal lymph nodes, liver and placenta. BCoV was therefore hypothesized to play a role in the lethal pulmonary infection. Like the other CoVs, BCoV is able to cause different syndromes. Its role in calf diarrhea and in mild respiratory disease is well known: we report instead the involvement of this virus in a severe and fatal respiratory disorder, with symptoms and disease evolution resembling those of Severe Acute Respiratory Syndromes (SARS).

Indexed as

AnimalsCattleCattle DiseasesCoronavirus, BovineCoronavirus InfectionsDiarrheaDisease OutbreaksFecesFemaleItalyLung Diseases, InterstitialPhylogenyRespiratory Tract InfectionsRNA, ViralSevere Acute Respiratory SyndromeRNA, Viralbovine coronavirusinterstitial pneumoniaphylogenetic analysisreal time PCR

Identifiers

PMID33228210
PMCPMC7699522
OpenAlexW3101399067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.