Evidence map›Paper›PMID 33228195›Full record

ArticleInternational journal of molecular sciences2020

Aerobic Cytotoxicity of Aromatic

Aušra Nemeikaitė-Čėnienė, Jonas Šarlauskas, Lina Misevičienė, Audronė Marozienė, Violeta Jonušienė, Mindaugas Lesanavičius, Narimantas Čėnas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Kinetic and Potentiometric Characteristics of Ferredoxin: NADPInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Redox Proteomic Profile of Tirapazamine-Resistant Murine Hepatoma Cells.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Aušra Nemeikaitė-ČėnienėState Research Institute Center for Innovative Medicine, Santariškių St. 5, LT-08406 Vilnius, Lithuania.
Jonas ŠarlauskasInstitute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0003-4268-1716
Lina MisevičienėInstitute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Audronė MarozienėInstitute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Violeta JonušienėInstitute of Biosciences of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.ORCID 0000-0003-4614-3595
Mindaugas LesanavičiusInstitute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Narimantas ČėnasInstitute of Biochemistry of Vilnius University, Saulėtekio 7, LT-10257 Vilnius, Lithuania.
Vilnius University · LTState Research Institute Centre for Innovative Medicine · LT

Funding

European Science Foundation DOTSUT-34/09.3.3.-LMT-K712-01-0058
6 · The paper itself

Abstract

Derivatives of tirapazamine and other heteroaromatic

Indexed as

AerobiosisAnimalsAnti-Bacterial AgentsAntioxidantsAntiprotozoal AgentsCell Line, TumorCell SurvivalCyclic N-OxidesDicumarolEnzyme AssaysEnzyme InhibitorsFerredoxin-NADP ReductaseHCT116 CellsHepatocytesHumansKineticsAnti-Bacterial AgentsAntioxidantsAntiprotozoal AgentsCyclic N-OxidesDicumarolEnzyme InhibitorsFerredoxin-NADP ReductaseNAD(P)H Dehydrogenase (Quinone)NADPH-Ferrihemoprotein ReductaseNQO1 protein, ratProtozoan ProteinsTirapazaminecytotoxicityNAD(P)H:quinone oxidoreductaseoxidative stressreductive activationtirapazamine

Identifiers

PMID33228195
PMCPMC7699506
OpenAlexW3102819797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.