Evidence map›Paper›PMID 33228090›Full record

ArticleBiosensors2020

Developing Rapid Antimicrobial Susceptibility Testing for Motile/Non-Motile Bacteria Treated with Antibiotics Covering Five Bactericidal Mechanisms on the Basis of Bead-Based Optical Diffusometry.

Yao-Tzu Yang, Jhih-Cheng Wang, Han-Sheng Chuang

Abstract read
In one paragraph

Article in Biosensors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. Regrowth ofEnvironmental science : water research & technology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yao-Tzu YangDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
Jhih-Cheng WangDepartment of Urology, Chi-Mei Medical Center, Tainan 71004, Taiwan.
Han-Sheng ChuangDepartment of Biomedical Engineering, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0002-7257-6565

Funding

Ministry of Education, Taiwan Higher Education Sprout ProjectMinistry of Science and Technology 108-2628-E-006 -002 -MY3
6 · The paper itself

Abstract

Rapid antimicrobial susceptibility testing (AST) is an effective measure in the treatment of infections and the prevention of bacterial drug resistance. However, diverse antibiotic types and bacterial characteristics have formed complicated barriers to rapid diagnosis. To counteract these limitations, we investigated the interactions between antibiotic-treated bacteria and functionalized microbeads in optical diffusometry. The conjugation with bacteria increased the effective microbead complex size, thereby resulting in a temporal diffusivity change. The yielded data were sorted and analyzed to delineate a pattern for the prediction of antimicrobial susceptibility. The outcome showed that a completed rapid AST based on the trend of microbead diffusivity could provide results within 3 h (2 h measurement + 1 h computation). In this research, we studied four bacterial strains, including

Indexed as

Anti-Bacterial AgentsBacteriaBacterial LoadEscherichia coliHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMicrospheresPseudomonas aeruginosaStaphylococcus aureusAnti-Bacterial Agentsantibioticsantimicrobial susceptibility testingbacteriaBrownian motionclinical samplemicrobeadoptical diffusometry

Identifiers

PMID33228090
PMCPMC7699397

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.