Evidence map›Paper›PMID 33228010›Full record

ReviewJournal of fungi (Basel, Switzerland)2020

Overview of Antifungal Drugs against Paracoccidioidomycosis: How Do We Start, Where Are We, and Where Are We Going?

Lívia do Carmo Silva, Amanda Alves de Oliveira, Dienny Rodrigues de Souza, Katheryne Lohany Barros Barbosa, Kleber Santiago Freitas E Silva, Marcos Antonio Batista Carvalho Júnior, Olívia Basso Rocha, Raisa Melo Lima, Thaynara Gonzaga Santos, Célia Maria de Almeida Soares and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Telomeric assemblies ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Polypeptides TargetingJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Exposure ofAntibiotics (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Proteomic Response ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Paracoccidioidomycosis Protective Immunity.Journal of fungi (Basel, Switzerland) · 2021
    Review
  12. Updates inJournal of fungi (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Lívia do Carmo SilvaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Amanda Alves de OliveiraLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Dienny Rodrigues de SouzaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0003-1683-1514
Katheryne Lohany Barros BarbosaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Kleber Santiago Freitas E SilvaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0001-5350-7313
Marcos Antonio Batista Carvalho JúniorLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0003-1513-3247
Olívia Basso RochaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0002-2094-6042
Raisa Melo LimaLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0003-1210-8302
Thaynara Gonzaga SantosLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Célia Maria de Almeida SoaresLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.ORCID 0000-0001-5378-9840
Maristela PereiraLaboratory of Molecular Biology, Institute of Biological Sciences, Federal University of Goiás, Goiânia 74690-900, GO, Brazil.
Universidade Federal de Goiás · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 001Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

Paracoccidioidomycosis is a neglected disease that causes economic and social impacts, mainly affecting people of certain social segments, such as rural workers. The limitations of antifungals, such as toxicity, drug interactions, restricted routes of administration, and the reduced bioavailability in target tissues, have become evident in clinical settings. These factors, added to the fact that Paracoccidioidomycosis (PCM) therapy is a long process, lasting from months to years, emphasize the need for the research and development of new molecules. Researchers have concentrated efforts on the identification of new compounds using numerous tools and targeting important proteins from

Indexed as

antifungalnanotechnologyParacoccidioidomycosispatent

Identifiers

PMID33228010
PMCPMC7712482
OpenAlexW3099337195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.