Evidence map›Paper›PMID 33227948›Full record

ReviewBiology2020

Insights on the Quest for the Structure-Function Relationship of the Mitochondrial Pyruvate Carrier.

José Edwin Neciosup Quesñay, Naomi L Pollock, Raghavendra Sashi Krishna Nagampalli, Sarah C Lee, Vijayakumar Balakrishnan, Sandra Martha Gomes Dias, Isabel Moraes, Tim R Dafforn, Andre Luis Berteli Ambrosio

Open access · goldAbstract readReview
In one paragraph

Review in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Journal of bacteriology · 2025
    Article
  2. Review
  3. Review
  4. Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes.Journal of chemical information and modeling · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

José Edwin Neciosup QuesñayBrazilian Biosciences National Laboratory, Center for Research in Energy and Materials, Campinas 13083-970, Brazil.
Naomi L PollockSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Raghavendra Sashi Krishna NagampalliBrazilian Biosciences National Laboratory, Center for Research in Energy and Materials, Campinas 13083-970, Brazil.
Sarah C LeeSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-0557-6266
Vijayakumar BalakrishnanSão Carlos Institute of Physics, University of São Paulo, São Carlos 13563-120, Brazil.
Sandra Martha Gomes DiasBrazilian Biosciences National Laboratory, Center for Research in Energy and Materials, Campinas 13083-970, Brazil.ORCID 0000-0002-1589-7856
Isabel MoraesMembrane Protein Laboratory, Diamond Light Source Limited, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.ORCID 0000-0002-7427-5467
Tim R DaffornSchool of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.
Andre Luis Berteli AmbrosioSão Carlos Institute of Physics, University of São Paulo, São Carlos 13563-120, Brazil.ORCID 0000-0002-9515-930X
University of Birmingham · GBBrazilian Biosciences National Laboratory · BRUniversidade de São Paulo · BRDiamond Light Source · GBUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Biotechnology and Biological Sciences Research Council BB/S008160/1Fundacao de Amparo a Pesquisa do Estado de Sao Paulo 2014/20673-2, 2017/11766-5, 2015/02734-7, 2019/02261-2, 2014/06954-9, 2017/02391-8, 2018/00492-4Wellcome Trust 20289/Z16/Z
6 · The paper itself

Abstract

The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated. An impressive amount of

Indexed as

functionmembrane proteinsmitochondrial pyruvate carrierstructure

Identifiers

PMID33227948
PMCPMC7699257
OpenAlexW3103056861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.