Evidence map›Paper›PMID 33227672›Full record

ArticleJournal of affective disorders2021

Early childhood psychosocial family risks and cumulative dopaminergic sensitizing score: Links to behavior problems in U.S. 9-year-olds.

Sari Mullola, Jeanne Brooks-Gunn, Marko Elovainio, Christian Hakulinen, Lisa M Schneper, Daniel A Notterman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Relationship between family risk factors and adolescent mental health.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sari MullolaColumbia University, Teachers College, National Center for Children and Families (NCCF), Thorndike Hall 525 West 120th Street, Box 39 New York, NY 10027, USA; Tampere University, Faculty of Education and Culture, Main Campus Virta, Åkerlundinkatu 5, P.O. Box 700, FI-33014 Tampere University, Finland; University of Helsinki, Faculty of Educational Sciences, Siltavuorenpenger 5A, P.O. Box 9, 00014 University of Helsinki, Finland. Electronic address: sari.mullola@tuni.fi.
Jeanne Brooks-GunnColumbia University, Teachers College, National Center for Children and Families (NCCF), Thorndike Hall 525 West 120th Street, Box 39 New York, NY 10027, USA; Columbia University, The College of Physicians and Surgeons, New York, NY 10027, USA. Electronic address: brooks-gunn@columbia.edu.
Marko ElovainioUniversity of Helsinki, Medical Faculty, Department of Psychology and Logopedics, Helsinki, Finland; Institute for Health and Welfare, P.O. Box 30, 00370 Helsinki, Finland. Electronic address: marko.elovainio@helsinki.fi.
Christian HakulinenUniversity of Helsinki, Medical Faculty, Department of Psychology and Logopedics, Helsinki, Finland. Electronic address: christian.hakulinen@helsinki.fi.
Lisa M SchneperDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA. Electronic address: lweis@princeton.edu.
Daniel A NottermanPrinceton University, 219 Lewis Thomas Laboratory, Princeton, NJ 08544, USA. Electronic address: dan1@princeton.edu.

Funding

Fragile Families and the Transition to AdulthoodR01HD036916 · NICHD · PRINCETON UNIVERSITY · PI Kathryn Edin, Jane Waldfogel · 1999 to 2026
$46.3M
Reciprocal Genetic-Environmental Interactions During Childhood and AdolescenceR01HD076592 · NICHD · PRINCETON UNIVERSITY · PI NOTTERMAN, DANIEL A. · 2013 to 2023
$6.8M
ECONOMIC STATUS, PUBLIC POLICY, AND CHILD NEGLECTR01HD039135 · NICHD · PRINCETON UNIVERSITY · PI PAXSON, CHRISTINA H · 2000 to 2004
$3.1M
Child Care and Parental Employment in Fragile FamiliesR01HD040421 · NICHD · COLUMBIA UNIVERSITY TEACHERS COLLEGE · PI BROOKS-GUNN, JEANNE · 2002 to 2006
$2.8M
Future of Families and Child Wellbeing Study Summer Data WorkshopR25HD074544 · NICHD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Amanda Geller, Julien O Teitler · 2013 to 2026
$1.5M
NICHD NIH HHS R01 HD036916NICHD NIH HHS R01 HD039135NICHD NIH HHS R01 HD040421NICHD NIH HHS R01 HD076592NICHD NIH HHS R25 HD074544
6 · The paper itself

Abstract

backgroundWe examined, (a) whether in early childhood exposure to risky family environment in different domains (socioeconomic, mental, parenting practices, health behavior, and child-related risks) and accumulatively across various domains (cumulative risk) is associated with child's problem behavior at age 9, and (b) whether the association is more pronounced in children carrying cumulative dopaminergic sensitizing genotype or living in low-income families.

methodsParticipants were 2,860 9-year old children (48% females; 48% Black) and their mothers from the 'Fragile Families and Child Wellbeing Study', a probability birth cohort from large U.S. cities. Mothers responded to questions on child's problem behavior (CBCL). Children responded to questions about their vandalism and substance use.

resultsCumulative family risk was associated with higher internalizing and externalizing behavior and higher vandalism and substance use. All domain-specific risk clusters were associated with higher internalizing behavior and, with the exception of child-related risk, with higher externalizing behavior. Mental health risks, risky parenting practices, and risky health behavior were associated with higher vandalism. Risky parenting practices were associated with higher substance use. The associations were robust to adjustment for cumulative dopaminergic sensitizing genotype. No G x E interactions with dopaminergic genotype and family SES were observed. LIMITATIONS: Sample size was relatively small for genetic analysis and polygenic risk scores were not available.

conclusionsExposure to cumulative psychosocial family risks from early childhood is associated with early indicators of problem behavior in adolescence.

Indexed as

Child Behavior DisordersProblem BehaviorAdolescentBlack or African AmericanChildChild BehaviorChild, PreschoolFemaleHumansMaleMothersParentingAntisocial behaviorCumulative dopaminergic sensitizing scoreCumulative family riskDomain-specific family riskProblem behavior

Identifiers

PMID33227672
PMCPMC7839973

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.