Evidence map›Paper›PMID 33227640›Full record

ArticleThe International journal on drug policy2021

Poly-prescription drug misuse across the life course: Prevalence and correlates across different adult age cohorts in the U.S.

Jason A Ford, Ty S Schepis, Sean Esteban McCabe

Open access · greenAbstract read
In one paragraph

Article in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jason A FordDepartment of Sociology, University of Central Florida, Orlando, FL United States. Electronic address: jason.ford@ucf.edu.
Ty S SchepisDepartment of Psychology, Texas State University, San Marcos, TX United States.
Sean Esteban McCabeCenter for the Study of Drugs, Alcohol, Smoking and Health, School of Nursing, University of Michigan, Ann Arbor, MI, United States; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI, United States; Institute for Research on Women and Gender, University of Michigan, Ann Arbor, MI, United States; Institute for Social Research, University of Michigan, Ann Arbor, MI, United States.
Texas State University · USUniversity of Central Florida · USUniversity of Michigan–Ann Arbor · US

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Prescription Drug Misuse Characteristics in Adolescents and Young Adults: Influence of School EnrollmentR01DA043691 · NIDA · TEXAS STATE UNIVERSITY · PI TY Stephen SCHEPIS · 2017 to 2026
$1.8M
Sexual Orientation, Discrimination, and Health Disparities in DSM-5 Alcohol Use DisordersR01AA025684 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2018 to 2020
$855k
Health, Stress, and Tobacco Use Disparities among Sexual Minority PopulationsR01CA212517 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCABE, SEAN ESTEBAN · 2017 to 2019
$721k
Nonmedical prescription drug misuse among US older adults: subtypes,motives, and diversion sourcesR01DA042146 · NIDA · TEXAS STATE UNIVERSITY · PI SCHEPIS, TY STEPHEN · 2017 to 2021
$548k
NCI NIH HHS R01 CA212517NIAAA NIH HHS R01 AA025684NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA042146NIDA NIH HHS R01 DA043691
6 · The paper itself

Abstract

backgroundMost research on prescription drug misuse (PDM) focuses on the misuse of specific classes of psychoactive prescription drugs among adolescents or young adults. The current research addressed important gaps in the literature by assessing poly-prescription drug misuse (poly-PDM), the misuse of more than one class of psychoactive prescription drug, across different adult age cohorts.

methodsWe used the 2015-2018 National Survey on Drug Use and Health to examine the prevalence of past-year poly-PDM and specific combinations of PDM. Multinomial logistic regression was used to identify demographic, health-related factors, and substance use behaviors that were significantly associated with poly-PDM.

resultsThe prevalence of poly-PDM decreases with age and is common among individuals who engage in PDM. Slightly more than one in four respondents in age cohorts 18-25 (31.66%, 95% CI = 30.35, 33.00) and 26-34 (29.92%, 95% CI = 25.82, 30.12) who engage in PDM, misused more than one class of prescription drug. Additionally, poly-PDM was identified as a high-risk type of PDM as roughly 60% of adults younger than 65 who endorse poly-PDM reported having a substance use disorder (SUD). While certain characteristics (i.e., race/ethnicity, marital status, depression, suicidal ideation, illegal drug use, and SUD) were consistently associated with poly-PDM across age cohorts, other characteristics (i.e., sexual identity, income, and justice involvement) varied across age cohorts. Finally, a comparison of poly-PDM to single PDM showed, in all age cohorts, that having an SUD was associated with an increased likelihood of poly-PDM, while Black adults were less likely than whites to report poly-PDM.

conclusionsBy identifying prevalence and correlates of poly-PDM across adult age cohorts, the current research has significant implications. Understanding stability and heterogeneity in the characteristics associated with poly-PDM should inform interventions, identify at-risk groups, and shape public health approaches to dealing with high-risk substance use behavior.

Indexed as

Prescription Drug MisusePrescription DrugsSubstance-Related DisordersAdolescentEthnicityHumansPrevalenceYoung AdultPrescription DrugsLife coursePolysubstance usePrescription drug misuse

Identifiers

PMID33227640
PMCPMC8005409
OpenAlexW3107034171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.