Evidence map›Paper›PMID 33227628›Full record

ArticleCancer epidemiology2020

The prevalence of chronic conditions in patients diagnosed with one of 29 common and rarer cancers: A cross-sectional study using primary care data.

Minjoung Monica Koo, Ruth Swann, Sean McPhail, Gary A Abel, Cristina Renzi, Greg P Rubin, Georgios Lyratzopoulos

Open access · hybridAbstract read
In one paragraph

Article in Cancer epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  3. Geographic variation in surgery rates among older patients with early (ER positive HER2 negative) breast cancer: Influence of cardiovascular disease and comorbidities: A national registry dataset analysis.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Minjoung Monica KooUniversity College London, 1-19 Torrington Place, London WC1E 6BT, UK; National Cancer Registration and Analysis Service, Public Health England, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, UK. Electronic address: Monica.koo@ucl.ac.uk.
Ruth SwannNational Cancer Registration and Analysis Service, Public Health England, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, UK; Cancer Research UK, 2 Redman Place, London, E20 1JQ, UK.
Sean McPhailUniversity College London, 1-19 Torrington Place, London WC1E 6BT, UK; National Cancer Registration and Analysis Service, Public Health England, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, UK.
Gary A AbelUniversity of Exeter Medical School, St Luke's Campus, Heavitree Road, Exeter, EX1 2LU, UK.
Cristina RenziUniversity College London, 1-19 Torrington Place, London WC1E 6BT, UK.
Greg P RubinInstitute of Health and Society, Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.
Georgios LyratzopoulosUniversity College London, 1-19 Torrington Place, London WC1E 6BT, UK; National Cancer Registration and Analysis Service, Public Health England, Wellington House, 133-155 Waterloo Road, London, SE1 8UG, UK.
National Cancer Registration Service · GBUniversity College London · GBRoyal Victoria Infirmary · GBUniversity of Exeter · GB

Funding

Cancer Research UK 18180Cancer Research UK C18081/A18180Cancer Research UK C8640/A23385
6 · The paper itself

Abstract

backgroundPre-existing chronic conditions (morbidities) influence the diagnosis and management of cancer. The prevalence of specific morbidities in patients diagnosed with common and rarer cancers is inadequately described.

methodsUsing data from the English National Cancer Diagnosis Audit 2014, we studied 11 pre-existing morbidities recorded as yes/no items by participating general practitioners based on information included in primary care records. We examined the number and type of morbidities across socio-demographic and cancer site strata, and subsequently estimated observed and age/sex standardised prevalence of each morbidity by cancer.

resultsOver three-quarters (77 %; 11,429/14,774) of non-screen-detected patients had at least one chronic condition before diagnosis, while nearly half (47 %) had two or more. Hypertension (39 %) and physical disability (2%) were the most and least common conditions. Male, older and more socio-economically deprived patients were more likely to have at least one morbidity (p < 0.001 for all between variable group comparisons). For most morbidities, the standardised prevalence was similar across different cancers with a few exceptions, including respiratory disease prevalence being greatest among lung cancer patients and diabetes prevalence being greatest among liver, pancreatic, and endometrial cancer patients.

conclusionsMost cancer patients have at least one morbidity, while almost one in two have two or more. The findings highlight the need to take certain morbidity- and cancer-site combinations into account when examining associations between morbidity and cancer outcomes.

Indexed as

AdultAgedAged, 80 and overChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMiddle AgedNeoplasmsPrevalencePrimary Health CareCancer outcomesComorbiditiesEpidemiologyLong-term conditionsOncology

Identifiers

PMID33227628
PMCPMC7768190
OpenAlexW3109612593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.