Evidence map›Paper›PMID 33227180›Full record

ArticleJournal of Korean Neurosurgical Society2021

Association between Histone Deacetylase 9 Gene Polymorphism and Stroke in Chinese Han Population.

Xitong Yang, Hongyang Xu, Dan Liu, Rong Ma, Yuanyuan Zhang, Guangming Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean Neurosurgical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xitong YangGenetic Testing Center, The First Affiliated hospital of Dali University, Dali, China.
Hongyang XuDeparment of Encephalopathy, Hospital of Traditional Chinese Medicine, Guangde, China.
Dan LiuGenetic Testing Center, The First Affiliated hospital of Dali University, Dali, China.
Rong MaGenetic Testing Center, The First Affiliated hospital of Dali University, Dali, China.
Yuanyuan ZhangGenetic Testing Center, The First Affiliated hospital of Dali University, Dali, China.
Guangming WangGenetic Testing Center, The First Affiliated hospital of Dali University, Dali, China.
Dali University · CNAnyang Hospital of Traditional Chinese Medicine · CN

Funding

Colleges joint specific project in Yunnan Province 2019FH001-(020)National Natural Science Foundation of China 81360206Reserve Talents of Academic and TechnicalLeaders of Young and Middle-aged People in Yunnan Province 2014HB025Scientific research fund project of Yunnan education department 2019J0775
6 · The paper itself

Abstract

objectiveTo explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region.

methodsThis study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology and multivariate logistic regression were performed.

resultsIn the case group, there was no polymorphism of rs1060499865 observed in the two groups; whereas on the rs723296 locus the frequencies of C allele and TC genotype were significantly higher than that in the control group, alleles C and T were associated with a 2.158-fold increase in IS risk, and genotypes TC and TT were associated with a 2.269-fold increase in IS risk. The locus rs957960 exhibited no significant difference between the two groups.

conclusionAn association between rs723296 and the risk of IS was found in the Chinese Han population in Dali region. No significant association was found between rs1060499865, rs957960 and IS in the Chinese Han population in Dali region.

Indexed as

HDAC9 proteinPolymorphismStroke

Identifiers

PMID33227180
PMCPMC7969036
OpenAlexW3106544516

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.