Evidence map›Paper›PMID 33226886›Full record

ArticleLymphatic research and biology2021

Involvement of Sigma Receptor-1 in Lymphatic Endothelial Barrier Integrity and Bioenergetic Regulation.

Zeinab Y Motawe, Salma S Abdelmaboud, Jerome W Breslin

Open access · greenAbstract read
In one paragraph

Article in Lymphatic research and biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Heavy alcohol consumption attenuates human mesenteric artery responsiveness to sigma receptor-1 ligands.American journal of physiology. Heart and circulatory physiology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zeinab Y MotaweDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Salma S AbdelmaboudDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Jerome W BreslinDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
University of South Florida · US

Funding

S1P-fluid therapy to reduce hemorrhagic shock & intoxication-induced injuryR01GM120774 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI BRESLIN, JEROME W · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM120774
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Endothelium, LymphaticReceptors, sigmaCells, CulturedEndothelial CellsEndothelium, VascularEnergy MetabolismHumansReceptors, sigmaendothelial bioenergeticslymphatic endothelial permeabilitySIGMAR1sigma receptors

Identifiers

PMID33226886
PMCPMC8220569
OpenAlexW3110062604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.