Evidence map›Paper›PMID 33226835›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Stuck in a Moment: Does Abnormal Persistence of Epithelial Progenitors Drive Pulmonary Fibrosis?

Vincent C Auyeung, Dean Sheppard

Abstract readEditorialComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Biomarkers Unveil Insights into Pathology of Transitional Epithelial States in Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2024
    Article
  5. Article
  6. Article
  7. Nestin promotes pulmonary fibrosisThe European respiratory journal · 2022
    Article
  8. IRE1α drives lung epithelial progenitor dysfunction to establish a niche for pulmonary fibrosis.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Vincent C AuyeungDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine University of California, San Francisco San Francisco, California.ORCID 0000-0001-6273-1595
Dean SheppardDivision of Pulmonary, Critical Care, Allergy, and Sleep Medicine University of California, San Francisco San Francisco, California.ORCID 0000-0002-6277-2036

Funding

IRE1α mediated dysregulation of the pulmonary epithelium in lung fibrosisK08HL157654 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AUYEUNG, VINCENT CHURK-MAN · 2021 to 2025
$874k
The unfolded protein response and TGF-Beta signaling in pulmonary fibrosisF32HL145990 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AUYEUNG, VINCENT CHURK-MAN · 2019 to 2020
$137k
NHLBI NIH HHS F32 HL145990NHLBI NIH HHS K08 HL157654
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary FibrosisAlveolar Epithelial CellsHumans

Identifiers

PMID33226835
PMCPMC7958518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.