Evidence map›Paper›PMID 33226834›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations.

Olivia C Leavy, Shwu-Fan Ma, Philip L Molyneaux, Toby M Maher, Justin M Oldham, Carlos Flores, Imre Noth, R Gisli Jenkins, Frank Dudbridge, Louise V Wain and 1 more

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Observational
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  16. A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities.American journal of respiratory and critical care medicine · 2023
    Article
  17. Article
  18. Proprotein Convertase Subtilisin/Kexin Type 6: A Risk Factor for Survival in Pulmonary Fibrosis?American journal of respiratory and critical care medicine · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olivia C LeavyUniversity of Leicester Leicester, United Kingdom.ORCID 0000-0002-1503-5535
Shwu-Fan MaUniversity of Virginia Charlottesville, Virginia.ORCID 0000-0002-3058-9480
Philip L MolyneauxRoyal Brompton Hospital London, United Kingdom.ORCID 0000-0003-1301-8800
Toby M MaherRoyal Brompton Hospital London, United Kingdom.ORCID 0000-0001-7192-9149
Justin M OldhamUniversity of California Davis Davis, California.ORCID 0000-0003-4957-8869
Carlos FloresHospital Universitario Ntra. Sra. de Candelaria Santa Cruz de Tenerife, Spain.ORCID 0000-0001-5352-069X
Imre NothUniversity of Virginia Charlottesville, Virginia.
R Gisli JenkinsUniversity of Nottingham Nottingham, United Kingdom.ORCID 0000-0002-7929-2119
Frank DudbridgeUniversity of Leicester Leicester, United Kingdom.ORCID 0000-0002-8817-8908
Louise V WainUniversity of Leicester Leicester, United Kingdom.ORCID 0000-0003-4951-1867
Richard J AllenUniversity of Leicester Leicester, United Kingdom.ORCID 0000-0002-8450-3056

Funding

Architectural structure and regulation of TOLLIP in IPFR01HL130796 · NHLBI · UNIVERSITY OF VIRGINIA · PI NOTH, IMRE · 2016 to 2019
$3.1M
1/2 Prospective tReatment EffiCacy in IPF uSlng genOtype for Nac Selection (PRECISIONS) trial and Molecular Endophenotyping in Idiopathic Pulmonary Fibrosis and Interstitial Lung Diseases studyUG3HL145266 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARTINEZ, FERNANDO J, NOTH, IMRE · 2019 to 2019
$977k
Elucidating the Genomic Determinants of Outcomes in Idiopathic Pulmonary FibrosisK23HL138190 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, JUSTIN M · 2017 to 2021
$914k
Department of Health CS-2013-13-017HSRD VA CDA 13-017Medical Research Council G0901226NHLBI NIH HHS K23 HL138190NHLBI NIH HHS R01 HL130796NHLBI NIH HHS UG3 HL145266
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic LociAdultAgedAged, 80 and overEuropeFemaleGenetic Predisposition to DiseaseHumansIdiopathic Pulmonary FibrosisMiddle AgedRisk Assessment

Identifiers

PMID33226834
PMCPMC7958523

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.