Evidence map›Paper›PMID 33226684›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2021

Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response.

Sara Querido, Rita Calça, André Weigert, Diogo Francisco, Teresa Adragão, Maria Ana Pessanha, Perpétua Gomes, Luís Rodrigues, João M Figueira, Conceição Cardoso and 1 more

Abstract readCase Reports
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. TTV viral load as a predictor of antibody response to SARS COV-2 vaccination.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sara QueridoDepartment of Nephrology, Unit of Renal Transplantation, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.ORCID https://orcid.org/0000-0003-2325-1817
Rita CalçaDepartment of Nephrology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.ORCID https://orcid.org/0000-0001-8960-2363
André WeigertDepartment of Nephrology, Unit of Renal Transplantation, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.
Diogo FranciscoDepartment of Nephrology, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.
Teresa AdragãoDepartment of Nephrology, Unit of Renal Transplantation, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.
Maria Ana PessanhaDepartment of Clinical Pathology, Laboratory of Clinical Microbiology and Molecular Biology, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal.
Perpétua GomesDepartment of Clinical Pathology, Laboratory of Clinical Microbiology and Molecular Biology, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal.
Luís RodriguesDepartment of Clinical Pathology, Laboratory of Biochemistry, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal.
João M FigueiraDepartment of Clinical Pathology, Laboratory of Biochemistry, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal.
Conceição CardosoDepartment of Clinical Pathology, Laboratory of Biochemistry, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal.
Domingos MachadoDepartment of Nephrology, Unit of Renal Transplantation, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Carnaxide, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplant (KT) recipients are at an increased risk for severe COVID-19 because of their immunosuppressed state. A 42-year-old KT patient was diagnosed with COVID-19 three months after KT. Despite lymphopenia and several risk factors, he had a mild disease course. Nasopharyngeal real-time reverse transcriptase polymerase chain reaction for SARS-CoV-2 became negative 48 days after detection. SARS-CoV-2 IgG antibodies became negative after day 40. TTV DNA load increased with the onset COVID-19 and reduced after its resolution. This is the first report where TTV DNA load was measured during the course of COVID-19.

Indexed as

Immunocompromised HostKidney TransplantationAdultAntibodies, ViralComorbidityCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingDiabetes MellitusDNA, ViralDNA Virus InfectionsGlucocorticoidsGraft RejectionHumansHypertensionImmunoglobulin GAntibodies, ViralDNA, ViralGlucocorticoidsImmunoglobulin GImmunoglobulin MImmunosuppressive AgentsMycophenolic AcidPrednisoloneTacrolimusCOVID-19kidney transplantSARS-CoV-2torquetenovirus

Identifiers

PMID33226684
PMCPMC7744855

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.