Evidence map›Paper›PMID 33226597›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Cellular and Biochemical Analysis of Bronchoalveolar Lavage Fluid from Murine Lungs.

Rama Satyanarayana Raju Kalidhindi, Nilesh Sudhakar Ambhore, Venkatachalem Sathish

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 35 citations in OpenAlex.

  1. Redox protection by bacterial glutathione peroxidase drives virulence inRedox report : communications in free radical research · 2026
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  17. Juglans regiaJournal of tropical medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rama Satyanarayana Raju KalidhindiDepartment of Pharmaceutical Sciences, College of Health Professions, School of Pharmacy, North Dakota State University, Fargo, ND, USA.
Nilesh Sudhakar AmbhoreDepartment of Pharmaceutical Sciences, College of Health Professions, School of Pharmacy, North Dakota State University, Fargo, ND, USA.
Venkatachalem SathishDepartment of Pharmaceutical Sciences, College of Health Professions, School of Pharmacy, North Dakota State University, Fargo, ND, USA. s.venkatachalem@ndsu.edu.
North Dakota State University · US

Funding

Kisspeptins in the AirwayR01HL146705 · NHLBI · NORTH DAKOTA STATE UNIVERSITY · PI VENKATACHALEM, SATHISH · 2020 to 2024
$2.2M
Estrogen Receptor Signaling in Airway InflammationR01HL123494 · NHLBI · NORTH DAKOTA STATE UNIVERSITY · PI VENKATACHALEM, SATHISH · 2015 to 2019
$1.9M
NHLBI NIH HHS R01 HL123494NHLBI NIH HHS R01 HL146705
6 · The paper itself

Abstract

Bronchoalveolar lavage (BAL) is a technique used to collect the contents of the airways. The fluid recovered, called BAL fluid (BALF), serves as a dynamic tool to identify various disease pathologies ranging from asthma to infectious diseases to cancer in the lungs. A wide array of tests can be performed with BALF, including total and differential leukocyte counts (DLC), enzyme-linked immunosorbent assays (ELISA) or flow-cytometric quantitation of inflammatory mediators, such as cytokines, chemokines and adhesion molecules, and assessment of nitrate and nitrite content for estimation of nitric oxide synthase (NOS) activity. Here, we describe a detailed procedure for the collection of BALF for a variety of downstream usages, including DLC by cytological and flow-cytometry-based methods, multiplex cytokine analysis by flow cytometry, and NOS activity analysis by determining nitrate and nitrite levels.

Indexed as

AnimalsBasophilsBronchoalveolar Lavage FluidCytokinesEnzyme-Linked Immunosorbent AssayEosinophilsFlow CytometryHumansLeukocyte CountLungMacrophages, AlveolarMiceMonocytesNeutrophilsNitric Oxide SynthaseTracheostomyCytokinesNitric Oxide SynthaseCytokinesDifferential leukocyte countFlow cytometryNitric oxide synthaseTracheostomy

Identifiers

PMID33226597
PMCPMC7780416
OpenAlexW3109591212

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.