Evidence map›Paper›PMID 33226567›Full record

ArticleJournal of robotic surgery2021

Comparison of long-term outcomes in a 10-year experience of robotic cystectomy vs. open cystectomy.

Kevan L Ip, Juan F Javier-DesLoges, Cynthia Leung, James Nie, Ghazal Khajir, Cayce B Nawaf, Jamil Syed, James S Rosoff, Thomas V Martin, David G Hesse

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of robotic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Robot-assisted radical cystectomy: Where we are in 2023.Investigative and clinical urology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Kevan L IpDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
Juan F Javier-DesLogesDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-1120-9144
Cynthia LeungDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
James NieDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
Ghazal KhajirDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
Cayce B NawafDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
Jamil SyedDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
James S RosoffDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
Thomas V MartinDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA.
David G HesseDepartment of Urology, Yale University School of Medicine, P.O. Box 208058, New Haven, CT, USA. david.hesse@yale.edu.
Yale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the outcomes of robotic-assisted (RARC) vs. open radical cystectomy (ORC) at a single academic institution. We retrospectively identified patients undergoing radical cystectomy for urothelial carcinoma of the bladder at our institution from 2007 to 2017. Data collected included age, sex, Body Mass Index (BMI), Charlson Age-Adjusted Comorbidity Index (CCI), final pathologic stage, surgical margins, lymph-node yield, estimated blood loss (EBL), 90-day complication rate, and length of stay (LOS). We evaluated overall survival (OS) and recurrence-free survival (RFS). Multivariable Cox proportional hazard models were used to adjust for covariates. We identified 232 patients (73 RARC, 159 ORC) who underwent radical cystectomy. Patients who underwent RARC were older (71.8 vs. 67.5, p < 0.05) and had higher CCI scores (6.2 vs. 5.3, p < 0.05). In comparing perioperative outcomes, RARC patients had lower EBL (500 vs. 850, p < 0.01), lower blood transfusion rate (p < 0.01), and lower lymph-node yield (12 vs. 20, p < 0.01), and higher ICU admission rate (29% vs. 16% p < 0.01). There was no difference in BMI (p = 0.93), sex (p = 0.28), final pathological stage (p = 0.35), positive surgical margins (p = 0.47), complications (p = 0.58), or LOS (p = 0.34). Kaplan-Meier analysis showed no difference in OS (p = 0.26) or RFS (p = 0.86). There was no difference in restricted mean survival time for OS (53 vs. 56 months, p = 0.81) or for RFS (65 vs. 64 months, p = 0.90). Cox multivariate regression models showed that surgical approach does not have a significant impact on OS (p = 0.46) or RFS (p = 0.35). Our study indicates that in our 10-year experience, patients undergoing there was no difference between RARC and ORC patients with respect to OS and RFS despite being older and having more comorbidities. Our work supports the importance of patient selection to optimize outcomes.

Indexed as

Carcinoma, Transitional CellRobotic Surgical ProceduresUrinary Bladder NeoplasmsCystectomyHumansPostoperative ComplicationsRetrospective StudiesTreatment OutcomeBladder cancerOpen radical cystectomyRadical cystectomyRobot-assisted radical cystectomy

Identifiers

PMID33226567
OpenAlexW3108114144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.