Evidence map›Paper›PMID 33226370›Full record

SynthesisAging2020

A systematic review and network meta-analysis of single nucleotide polymorphisms associated with pancreatic cancer risk.

Zhuo-Miao Ye, Li-Juan Li, Ming-Bo Luo, Hong-Yuan Qing, Jing-Hui Zheng, Chi Zhang, Yun-Xin Lu, You-Ming Tang

Open access · greenAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. The Association ofInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhuo-Miao YeDepartment of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China; Ruikang School of Clinical Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China.
Li-Juan LiThe First Clinical Faculty of Guangxi University of Chinese Medicine, Guangxi University of Chinese Medicine, Nanning 530222, China.
Ming-Bo LuoRuikang School of Clinical Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China.
Hong-Yuan QingRuikang School of Clinical Medicine, Guangxi University of Chinese Medicine, Nanning 530001, China.
Jing-Hui ZhengDepartment of Cardiology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China.
Chi ZhangGraduate School, Guangxi University of Chinese Medicine, Nanning 530001, Guangxi, China.
Yun-Xin LuDepartment of Oncology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China.
You-Ming TangDepartment of Gastroenterology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Guangxi University of Chinese Medicine · CNGuangxi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this meta-analysis, we systematically investigated the correlation between single nucleotide polymorphisms (SNPs) and pancreatic cancer (PC) risk. We searched PubMed, Network Science, EMBASE, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Science and Technology Periodical Database (VIP), and Wanfang databases up to January 2020 for studies on PC risk-associated SNPs. We identified 45 case-control studies (36,360 PC patients and 54,752 non-cancer individuals) relating to investigations of 27 genes and 54 SNPs for this meta-analysis. Direct meta-analysis followed by network meta-analysis and Thakkinstian algorithm analysis showed that homozygous genetic models for

Indexed as

CTLA-4 AntigenGenetic Predisposition to DiseaseHumansPancreatic NeoplasmsPolymorphism, Single NucleotideReceptors, CalcitriolTumor Suppressor Protein p53CTLA-4 AntigenCTLA4 protein, humanReceptors, CalcitriolTP53 protein, humanTumor Suppressor Protein p53VDR protein, humanFPRPnetwork meta-analysispancreatic cancersingle nucleotide polymorphisms

Identifiers

PMID33226370
PMCPMC7803556
OpenAlexW3106730845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.