ArticleeLife2020
Chimpanzee brain morphometry utilizing standardized MRI preprocessing and macroanatomical annotations.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 47 citations in OpenAlex.
- CIVET-Chimp: An automated pipeline for MRI-based cortical surface extraction in chimpanzees.Neuroimage. Reports · 2026Article
- Heritability of gray matter volume and asymmetry in chimpanzees (Pan troglodytes) and their association to cognitive abilities and tool use.Brain structure & function · 2025Article
- Oro-facial and manual motor functions are differentially associated with short-fiber white matter connectivity within the chimpanzee "homunculus".Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Neuroimaging and immunofluorescence of the Pseudopus apodus brain: unraveling its structural complexity.Brain structure & function · 2025Article
- Long arcuate fascicle in wild and captive chimpanzees as a potential structural precursor of the language network.Nature communications · 2025Article
- Individual variation in the chimpanzee arcuate fasciculus predicts vocal and gestural communication.Nature communications · 2025Article
- Article
- The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans.Innovation (Cambridge (Mass.)) · 2025Article
- Enlargement of the human prefrontal cortex and brain mentalizing network: anatomically homogenous cross-species brain transformation.Brain structure & function · 2025Article
- Corpus callosum microstructure in chimpanzees (pan troglodytes): associations with age, handedness and cognition.Frontiers in aging neuroscience · 2025Article
- Assessment of MGMT promoter methylation status in glioblastoma using deep learning features from multi-sequence MRI of intratumoral and peritumoral regions.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- Comparative analysis of the chimpanzee and human brain superficial structural connectivities.Brain structure & function · 2024Article
- The uniqueness of human vulnerability to brain aging in great ape evolution.Science advances · 2024Article
- Comparative Analysis of Human-Chimpanzee Divergence in Brain Connectivity and its Genetic Correlates.bioRxiv : the preprint server for biology · 2024Article
- In vivo mapping of the deep and superficial white matter connectivity in the chimpanzee brain.NeuroImage · 2023Article
- Systematic cortical thickness and curvature patterns in primates.NeuroImage · 2023Article
- Neuroanatomical asymmetry in the canine brain.Brain structure & function · 2023Article
- Morphological evolution of language-relevant brain areas.PLoS biology · 2023Article
- Sulcal morphology of posteromedial cortex substantially differs between humans and chimpanzees.Communications biology · 2023Article
- Age differences in cortical thickness and their association with cognition in chimpanzee (Pan troglodytes).Neurobiology of aging · 2023Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 3 countries.
Funding
Abstract
Chimpanzees are among the closest living relatives to humans and, as such, provide a crucial comparative model for investigating primate brain evolution. In recent years, human brain mapping has strongly benefited from enhanced computational models and image processing pipelines that could also improve data analyses in animals by using species-specific templates. In this study, we use structural MRI data from the National Chimpanzee Brain Resource (NCBR) to develop the chimpanzee brain reference template Juna.Chimp for spatial registration and the macro-anatomical brain parcellation Davi130 for standardized whole-brain analysis. Additionally, we introduce a ready-to-use image processing pipeline built upon the CAT12 toolbox in SPM12, implementing a standard human image preprocessing framework in chimpanzees. Applying this approach to data from 194 subjects, we find strong evidence for human-like age-related gray matter atrophy in multiple regions of the chimpanzee brain, as well as, a general rightward asymmetry in brain regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.