Evidence map›Paper›PMID 33225998›Full record

ArticleeLife2020

The neural basis for a persistent internal state in

David Deutsch, Diego Pacheco, Lucas Encarnacion-Rivera, Talmo Pereira, Ramie Fathy, Jan Clemens, Cyrille Girardin, Adam Calhoun, Elise Ireland, Austin Burke and 14 more

Abstract readVideo-Audio Media
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Comparative neuroanatomy of emotion expression: from flies to humans.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  2. Fertility reversibly modulatesbioRxiv : the preprint server for biology · 2026
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  6. Organization and evolution of sex-biased gene expression inbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
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  10. Article
  11. Article
  12. Sexually-dimorphic neurons in theResearch square · 2025
    Article
  13. Article
  14. Sexually-dimorphic neurons in thebioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Inferring neural population codes forProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. High-resolution comparative single-cell transcriptomics ofbioRxiv : the preprint server for biology · 2025
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

David DeutschPrinceton Neuroscience Institute, Princeton University, Princeton, United States.ORCID https://orcid.org/0000-0002-8587-2435
Diego PachecoPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Lucas Encarnacion-RiveraPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Talmo PereiraPrinceton Neuroscience Institute, Princeton University, Princeton, United States.ORCID https://orcid.org/0000-0001-9075-8365
Ramie FathyPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Jan ClemensPrinceton Neuroscience Institute, Princeton University, Princeton, United States.ORCID http://orcid.org/0000-0003-4200-8097
Cyrille GirardinPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Adam CalhounPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Elise IrelandPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Austin BurkePrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Sven DorkenwaldPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Claire McKellarPrinceton Neuroscience Institute, Princeton University, Princeton, United States.ORCID https://orcid.org/0000-0002-3580-7336
Thomas MacrinaPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Ran LuPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Kisuk LeePrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Nico KemnitzPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Dodam IhPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Manuel CastroPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Akhilesh HalageriPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Chris JordanPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
William SilversmithPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Jingpeng WuPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
H Sebastian SeungPrinceton Neuroscience Institute, Princeton University, Princeton, United States.
Mala MurthyPrinceton Neuroscience Institute, Princeton University, Princeton, United States.ORCID https://orcid.org/0000-0003-3063-3389

Funding

Uncovering the Neural Mechanisms that Flexibly Link Sensory Processing to BehaviorR35NS111580 · NINDS · PRINCETON UNIVERSITY · PI Mala Murthy · 2019 to 2026
$5.0M
Crowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3M
Dissecting Sensorimotor Pathways Underlying Social Interactions: Models, Circuits, and BehaviorR01NS104899 · NINDS · PRINCETON UNIVERSITY · PI BIALEK, WILLIAM, MURTHY, MALA · 2018 to 2022
$2.4M
NIMH NIH HHS RF1 MH117815NINDS NIH HHS R01 NS104899NINDS NIH HHS R35 NS111580
6 · The paper itself

Abstract

Sustained changes in mood or action require persistent changes in neural activity, but it has been difficult to identify the neural circuit mechanisms that underlie persistent activity and contribute to long-lasting changes in behavior. Here, we show that a subset of Doublesex+ pC1 neurons in the

Indexed as

AnimalsBrainCourtshipDrosophila melanogasterFemaleMaleMicroscopy, ElectronMotor ActivityNeural PathwaysNeuronsconnectomicscourtshipD. melanogasterinternal stateneural circuitsneural imagingneurosciencesocial interaction

Identifiers

PMID33225998
PMCPMC7787663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.