ArticleJournal of cardiothoracic surgery2020
Langerhans cell histiocytosis of the rib presenting with pathological fracture: a case report.
Article in Journal of cardiothoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Pathological fractures revealing Langerhans cell histiocytosis in an elderly female: a rare case report.International journal of surgery case reports · 2026Article
- Isolated rib langerhans cell histiocytosis in an adult: a case report and literature review.Journal of cardiothoracic surgery · 2026Review
- An Adult Case of Chest Wall Langerhans Cell Histiocytosis Mimicking Malignancy and Responding to Targeted Therapy.Cureus · 2026Article
- Clinical outcomes of rib fracture stabilization and conservative treatment in a high-volume Asian trauma center: a propensity score-matched retrospective study.World journal of emergency surgery : WJES · 2025Article
- Benign tumors of the chest wall.Journal of thoracic disease · 2024Review
- Diagnosis and treatment of adult Langerhans cell histiocytosis in the rib: a case report and literature review.Annals of translational medicine · 2022Article
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6 authors.
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Abstract
introductionLangerhans cell histiocytosis (LCH) is a rare neoplastic hyperplasia with an unknown etiology. It is clinically rare for patients with solitary rib lesion and pathological fracture; moreover, its diagnosis and treatment are quite difficult. The purpose of this study is to present a case for the pathogenesis, clinical features, imaging, and treatment of this disease. CASE PRESENTATION: A 52-year-old female patient complained of left chest pain for one week. CT showed a fracture in the left 5th rib. The rib tumor was then resected and the surrounding muscles and soft tissues were accordingly resected. The patient was diagnosed with pathological rib fracture, and the patient was pathologically diagnosed with LCH. After surgery, no local recurrence or distant metastasis was reported during the two-year follow-up.
conclusionsLCH should be treated by observation, chemotherapy, radiotherapy, or surgery, or using a combination of several methods. Moreover, primary tumor should be considered when rib fracture without trauma and tumor metastasis.
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