ArticleOrthopaedic surgery2020
Diagnostic Value of MRI Lamellated Hyperintense Synovitis in Periprosthetic Infection of Hip.
Article in Orthopaedic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Diagnostic value of magnetic resonance imaging for patients with periprosthetic joint infection: a systematic review.BMC musculoskeletal disorders · 2023Pooled it
- Metal artifact reduction sequence MRI in hip periprosthetic joint infection management : a noninvasive reference for infection control before two-stage reimplantation.Bone & joint research · 2026Article
- Extensive Periprosthetic Lucencies and Acetabular Protrusio in a Hip Hemiarthroplasty: A Case Report.Cureus · 2026Article
- Combined use of 18 F-FDG PET/CT and MRI for evaluating infection status and clinical outcomes before reimplantation in two-stage revision arthroplasty.Journal of orthopaedic surgery and research · 2026Article
- Imaging in Periprosthetic Joint Infection Diagnosis: A Comprehensive Review.Microorganisms · 2024Review
- The role of advanced metal artifact reduction MRI in the diagnosis of periprosthetic joint infection.Skeletal radiology · 2024Review
- Imaging approach to prosthetic joint infection.Skeletal radiology · 2024Review
- Correction to "Diagnostic Value of MRI Lamellated Hyperintense Synovitis in Periprosthetic Infection of Hip".Orthopaedic surgery · 2024Article
- SimultaneousInternational orthopaedics · 2022Article
- Retrospective Study from a Single Center to Identify Risk Factors Associated with Reinfection in Patients Undergoing 2-Stage Revision Surgery for Periprosthetic Joint Infection.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Bone and Joint Infections: The Role of Imaging in Tailoring Diagnosis to Improve Patients' Care.Journal of personalized medicine · 2021Review
- Imaging update in arthroplasty.Journal of clinical orthopaedics and trauma · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the correlation between magnetic resonance imaging (MRI) lamellated hyperintense synovitis and periprosthetic infection of hip arthroplasty and estimate its value in the diagnosis of infection after hip replacement.
methodsA retrospective analysis of 50 patients who underwent MRI from January 2016 to June 2019 after hip replacement was performed. The MRI scanning was performed with a 1.5T clinical imaging unit using SEMAC protocols. A total of 25 patients (cohort 1) showed infected total hip arthroplasty, and 25 patients had non-infected arthroplasty as controls (cohort 2). Two musculoskeletal radiologists, blinded to the clinical diagnosis, reviewed all the images for the presence of lamellated hyperintense synovitis independently. The cases were rereviewed by each reader after 2 weeks. The sensitivity, specificity, positive predictive value, and negative predictive value were calculated using the first reads. The Kappa statistic was used to assess inter-observer and intra-observer reliability.
resultsThe incidence of lamellated hyperintense synovitis was 76%-88% in the experimental group and 8%-16% in the control group. The sensitivity of lamellated hyperintense synovitis for infection was 0.80-0.88 (95% confidence interval [CI]:0.59 - 0.97), the specificity was 0.84~0.92 (95% CI: 0.64 -0.99), the positive predictive value 0.83-0.92 (95% CI: 0.67 - 0.98), the negative predictive value 0.81 - 0.88 (95% CI: 0.65 - 0.96). The agreement between two readers was substantial (Kappa = 0.76, 95% CI: 0.58 - 0.94, P < 0.05). There were moderate inter-observer agreements for both readers, reader 1 (Kappa = 0.48, 95%CI: 0.23 - 0.72, P < 0.05) and reader 2 (Kappa = 0.44，95% CI: 0.19 - 0.69, P < 0.05).
conclusionIn this cohort, the presence of lamellated hyperintense synovitis in the MRI of hip arthroplasty showed high sensitivity and specificity for infection. This sign had substantial intra-observer reliability and moderate inter-observer reliability in the classification of the synovial pattern.
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